FBXW7 Vertebrate HGNC

Vertebrate Homology

Source

Alliance of Genome Resources

Comparative GO Graph (mouse, human, rat, zebrafish)

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences select all deselect all Go
human	FBXW7	HGNC:16712 (HGNC) 55294 (Entrez Gene) 606278 (OMIM) FBXW7 (Alliance of Genome Resources)	Chr4 q31.3	Chr4:152320544-152536092 (-) GRCh38	developmental delay, hypotonia, and impaired language	Q969H0 (UniProt \| EBI) NM_001013415 (RefSeq)
mouse	Fbxw7	MGI:1354695 (MGI) 50754 (Entrez Gene) Gene Tree Fbxw7 (Alliance of Genome Resources)	Chr3 37.7 cM	Chr3:84722575-84886505 (+) GRCm39		ENSMUSG00000028086 (Ensembl Gene Model) ENSMUSP00000103306 (Ensembl) ENSMUST00000107679 (Ensembl)
rat	Fbxw7	RGD:2321145 (Rat Genome Database) 100360914 (Entrez Gene) Fbxw7 (Alliance of Genome Resources)	Chr2			D3Z902 (UniProt \| EBI) NM_001419528 (RefSeq)
zebrafish	fbxw7	ZDB-GENE-090313-79 (Zebrafish Model Organism Database) 564991 (Entrez Gene) fbxw7 (Alliance of Genome Resources)	Chr1			XP_021326874 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
- human
- mouse
- rat
- zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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