BEST1 Vertebrate HGNC

Vertebrate Homology

Source

Alliance of Genome Resources

Comparative GO Graph (mouse, human, rat, zebrafish)

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences select all deselect all Go
human	BEST1	HGNC:12703 (HGNC) 7439 (Entrez Gene) 607854 (OMIM) BEST1 (Alliance of Genome Resources)	Chr11 q12.3	Chr11:61949821-61965515 (+) GRCh38	autosomal dominant vitreoretinochoroidopathy bestrophinopathy macular degeneration retinitis pigmentosa 50 vitelliform macular dystrophy	O76090 (UniProt \| EBI) NM_001363592 (RefSeq)
mouse	Best1	MGI:1346332 (MGI) 24115 (Entrez Gene) Gene Tree Best1 (Alliance of Genome Resources)	Chr19 6.24 cM	Chr19:9962538-9978997 (-) GRCm39	bestrophinopathy vitelliform macular dystrophy	ENSMUSG00000037418 (Ensembl Gene Model) ENSMUSP00000113053 (Ensembl) ENSMUST00000117346 (Ensembl)
rat	Best1	RGD:1311656 (Rat Genome Database) 293735 (Entrez Gene) Best1 (Alliance of Genome Resources)	Chr1 q43			NP_001011940 (RefSeq) NM_001011940 (RefSeq)
zebrafish	best1	ZDB-GENE-110411-214 (Zebrafish Model Organism Database) 560608 (Entrez Gene) best1 (Alliance of Genome Resources)	Chr25			XP_009295979 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
- human
- mouse
- rat
- zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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