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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human C5 HGNC:1331 (HGNC)
727 (Entrez Gene)
120900 (OMIM)
HGNC homology
Chr9 q33-q34 Chr9:120952335-121074925 (-)
Complement Component 5 Deficiency; C5D
Eculizumab, Poor Response to
P01031 (UniProt | EBI)
NM_001735 (RefSeq)
mouse Hc MGI:96031 (MGI)
15139 (Entrez Gene)
Gene Tree
Chr2 23.22 cM Chr2:34983331-35061438 (-)
OTTMUSG00000012274 (VEGA)
OTTMUSP00000013195 (VEGA)
OTTMUST00000029212 (VEGA)
chimpanzee C5 464703 (Entrez Gene)
Chr9 XP_009455472 (RefSeq)
rhesus macaque C5 700467 (Entrez Gene)
Chr15 XP_001095750 (RefSeq)
cattle C5 512045 (Entrez Gene)
Chr8 P12082 (UniProt | EBI)
NM_001166616 (RefSeq)
dog C5 474816 (Entrez Gene)
Chr11 XP_013973477 (RefSeq)
chicken C5 417122 (Entrez Gene)
Chr17 XP_415405 (RefSeq)
western clawed frog c5 100485433 (Entrez Gene)
ChrUN NP_001190988 (RefSeq)
NM_001204059 (RefSeq)
zebrafish c5 565774 (Entrez Gene)
Chr5 XP_001919226 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.01
The Jackson Laboratory