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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human MECOM HGNC:3498 (HGNC)
2122 (Entrez Gene)
165215 (OMIM)
HGNC homology
Chr3 q26.2 Chr3:169083499-169663786 (-)
Q03112 (UniProt | EBI)
NM_005241 (RefSeq)
mouse Mecom MGI:95457 (MGI)
14013 (Entrez Gene)
Gene Tree
HGNC homology
Chr3 12.66 cM Chr3:29951296-30548008 (-)
Otitis Media, Susceptibility to
OTTMUSG00000038143 (VEGA)
OTTMUSP00000055159 (VEGA)
OTTMUST00000098236 (VEGA)
chimpanzee MECOM 460837 (Entrez Gene)
Chr3 XP_516864 (RefSeq)
rhesus macaque MECOM 698603 (Entrez Gene)
Chr2 XP_001094041 (RefSeq)
cattle MECOM 532209 (Entrez Gene)
Chr1 XP_005201826 (RefSeq)
dog MECOM 488148 (Entrez Gene)
Chr34 XP_005639957 (RefSeq)
chicken MECOM 424997 (Entrez Gene)
Chr9 XP_004943558 (RefSeq)
western clawed frog mecom 100496511 (Entrez Gene)
ChrUN XP_012818870 (RefSeq)
zebrafish mecom 497407 (Entrez Gene)
Chr15 XP_009290130 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.0
The Jackson Laboratory