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Vertebrate Homology Class
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human CASP1 HGNC:1499 (HGNC)
834 (Entrez Gene)
147678 (OMIM)
Chr11 q23 Chr11:105025508-105035190 (-)
P29466 (UniProt | EBI)
NM_001223 (RefSeq)
mouse Casp1 MGI:96544 (MGI)
12362 (Entrez Gene)
Gene Tree
Chr9 2.46 cM Chr9:5298517-5307265 (+)
Dermatitis, Atopic
ENSMUSG00000025888 (Ensembl Gene Model)
ENSMUSP00000027015 (Ensembl)
ENSMUST00000027015 (Ensembl)
rat Casp1 25166 (Entrez Gene)
Chr8 q11 P43527 (UniProt | EBI)
NM_012762 (RefSeq)
chimpanzee CASP1 101058924 (Entrez Gene)
Chr11 XP_009422362 (RefSeq)
rhesus macaque CASP1 706568 (Entrez Gene)
Chr14 XP_001094943 (RefSeq)
cattle CASP1 514214 (Entrez Gene)
Chr15 XP_592026 (RefSeq)
dog CASP4 403724 (Entrez Gene)
Chr5 Q9MZV7 (UniProt | EBI)
NM_001003125 (RefSeq)
chicken CASP1 395764 (Entrez Gene)
Chr19 XP_003642432 (RefSeq)
NM_204924 (RefSeq)
western clawed frog LOC100491605 100491605 (Entrez Gene)
ChrUN XP_002935240 (RefSeq)
zebrafish caspa 57933 (Entrez Gene)
Chr16 NP_571580 (RefSeq)
NM_131505 (RefSeq)
caspbl 566185 (Entrez Gene)
Chr1 NP_001139064 (RefSeq)
NM_001145592 (RefSeq)
si:ch211-233g6.8 100333888 (Entrez Gene)
Chr1 XP_003197824 (RefSeq)
zgc:171731 563034 (Entrez Gene)
Chr7 NP_001103182 (RefSeq)
NM_001109712 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 5.21
The Jackson Laboratory