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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human CXCR4 HGNC:2561 (HGNC)
7852 (Entrez Gene)
162643 (OMIM)
Chr2 q21 Chr2:136114349-136118155 (-)
Whim Syndrome; WHIMS
P61073 (UniProt | EBI)
NM_003467 (RefSeq)
mouse Cxcr4 MGI:109563 (MGI)
12767 (Entrez Gene)
Gene Tree
Chr1 56.43 cM Chr1:128588199-128592293 (-)
Whim Syndrome; WHIMS
OTTMUSG00000020918 (VEGA)
OTTMUSP00000022912 (VEGA)
OTTMUST00000049443 (VEGA)
rat Cxcr4 60628 (Entrez Gene)
Chr13 q12 O08565 (UniProt | EBI)
NM_022205 (RefSeq)
chimpanzee CXCR4 450130 (Entrez Gene)
Chr2B P61072 (UniProt | EBI)
NM_001009047 (RefSeq)
rhesus macaque CXCR4 707329 (Entrez Gene)
Chr12 P79394 (UniProt | EBI)
NM_001042645 (RefSeq)
cattle CXCR4 281736 (Entrez Gene)
Chr2 P25930 (UniProt | EBI)
NM_174301 (RefSeq)
dog CXCR4 483900 (Entrez Gene)
Chr19 Q3LSL6 (UniProt | EBI)
NM_001048026 (RefSeq)
chicken CXCR4 395324 (Entrez Gene)
Chr7 NP_989948 (RefSeq)
NM_204617 (RefSeq)
western clawed frog cxcr4 100038176 (Entrez Gene)
ChrUN Q07FZ4 (UniProt | EBI)
NM_001097362 (RefSeq)
zebrafish cxcr4a 140747 (Entrez Gene)
Chr6 NP_571957 (RefSeq)
NM_131882 (RefSeq)
cxcr4b 114447 (Entrez Gene)
Chr9 NP_571909 (RefSeq)
NM_131834 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.03
The Jackson Laboratory