CXCR4 Vertebrate HGNC

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Vertebrate Homology

Source

Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
- human
- mouse
- rat
- zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 04/09/2024 MGI 6.23

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences select all deselect all Go
human	CXCR4	HGNC:2561 (HGNC) 7852 (Entrez Gene) 162643 (OMIM) CXCR4 (Alliance of Genome Resources)	Chr2 q22.1	Chr2:136114349-136119177 (-) GRCh38	acute myeloid leukemia leukopenia lymphoplasmacytic lymphoma osteoporosis osteosarcoma pancreatic adenocarcinoma prostate cancer stomach cancer T-cell acute lymphoblastic leukemia WHIM syndrome	P61073 (UniProt \| EBI) NM_001348056 (RefSeq)
mouse	Cxcr4	MGI:109563 (MGI) 12767 (Entrez Gene) Gene Tree Cxcr4 (Alliance of Genome Resources)	Chr1 56.43 cM	Chr1:128515936-128520030 (-) GRCm39	cardiomyopathy congestive heart failure WHIM syndrome	ENSMUSG00000045382 (Ensembl Gene Model) ENSMUSP00000053489 (Ensembl) ENSMUST00000052172 (Ensembl)
rat	Cxcr4	RGD:620465 (Rat Genome Database) 60628 (Entrez Gene) Cxcr4 (Alliance of Genome Resources)	Chr13 q13			O08565 (UniProt \| EBI) NM_022205 (RefSeq)
zebrafish	cxcr4a	ZDB-GENE-020102-1 (Zebrafish Model Organism Database) 140747 (Entrez Gene) cxcr4a (Alliance of Genome Resources)	Chr6			NP_571957 (RefSeq) NM_131882 (RefSeq)
zebrafish	cxcr4b	ZDB-GENE-010614-1 (Zebrafish Model Organism Database) 114447 (Entrez Gene) cxcr4b (Alliance of Genome Resources)	Chr9			NP_571909 (RefSeq) NM_131834 (RefSeq)