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Vertebrate Homology Class
Source
Class ID
HomoloGene (Release 68, May 6, 2014)
36030

Comparative GO Graph (mouse, human, rat)  
MGI Homology Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human C4A HGNC:1323 (HGNC)
720 (Entrez Gene)
120810 (OMIM)
Chr6 p21.3 Chr6:31982057-32002680 (+)
GRCh38
Complement Component 4a Deficiency; C4AD
Systemic Lupus Erythematosus; SLE
P0C0L4 (UniProt | EBI)
NM_007293 (RefSeq)
C4B HGNC:1324 (HGNC)
721 (Entrez Gene)
120820 (OMIM)
Chr6 p21.3 Chr6:32014795-32035418 (+)
GRCh38
Complement Component 4b Deficiency; C4BD
P0C0L5 (UniProt | EBI)
NM_001002029 (RefSeq)
mouse C4a MGI:98320 (MGI)
625018 (Entrez Gene)
Gene Tree
VISTA-Point
Chr17 18.37 cM Chr17:34809092-34823464 (-)
GRCm38
OTTMUSG00000033087 (VEGA)
NP_035543 (RefSeq)
OTTMUST00000082646 (VEGA)
C4b MGI:88228 (MGI)
12268 (Entrez Gene)
Gene Tree
VISTA-Point
Chr17 18.29 cM Chr17:34728380-34743882 (-)
GRCm38
Systemic Lupus Erythematosus; SLE
OTTMUSG00000037255 (VEGA)
OTTMUSP00000053641 (VEGA)
OTTMUST00000096077 (VEGA)
rat C4a 24233 (Entrez Gene)
Chr20 p12 P08649 (UniProt | EBI)
NM_031504 (RefSeq)
C4b 406161 (Entrez Gene)
Chr20 p12 NP_001002805 (RefSeq)
NM_001002805 (RefSeq)
chimpanzee C4A 462577 (Entrez Gene)
Chr6 XP_001162420 (RefSeq)
cattle C4A 280678 (Entrez Gene)
Chr23 P01030 (UniProt | EBI)
NM_001166485 (RefSeq)
dog C4A 481722 (Entrez Gene)
Chr12 XP_005627805 (RefSeq)
XM_538843 (RefSeq)
chicken C4 426611 (Entrez Gene)
Chr16 NP_001070701 (RefSeq)
NM_001077233 (RefSeq)
western clawed frog c4a 100135012 (Entrez Gene)
ChrUN NP_001107156 (RefSeq)
NM_001113684 (RefSeq)
zebrafish si:dkey-8k3.2 794635 (Entrez Gene)
Chr16 XP_001334640 (RefSeq)
MGI Homology Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
08/19/2014
MGI 5.19
The Jackson Laboratory