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HomoloGene Vertebrate Homology
Class ID
HomoloGene (Release 68, May 6, 2014)

Comparative GO Graph (mouse, human, rat)  
MGI HomoloGene Information
Species Symbol Gene Links Genetic Location Genome Coordinates
(mouse and human only)
Associated Human Diseases Sequences
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human SERPINE1 HGNC:8583 (HGNC)
5054 (Entrez Gene)
173360 (OMIM)
HGNC homology
Chr7 q22.1 Chr7:101127089-101139266 (+)
Plasminogen Activator Inhibitor-1 Deficiency
P05121 (UniProt | EBI)
NM_000602 (RefSeq)
mouse Serpine1 MGI:97608 (MGI)
18787 (Entrez Gene)
Gene Tree
HGNC homology
Chr5 76.16 cM Chr5:137061504-137072268 (-)
OTTMUSG00000054456 (VEGA)
OTTMUSP00000071541 (VEGA)
OTTMUST00000135048 (VEGA)
rat Serpine1 24617 (Entrez Gene)
Chr12 q11-q12 P20961 (UniProt | EBI)
NM_012620 (RefSeq)
chimpanzee SERPINE1 472467 (Entrez Gene)
Chr7 XP_527841 (RefSeq)
rhesus macaque SERPINE1 713883 (Entrez Gene)
Chr13 XP_001107647 (RefSeq)
cattle SERPINE1 281375 (Entrez Gene)
Chr25 P13909 (UniProt | EBI)
NM_174137 (RefSeq)
dog SERPINE1 403476 (Entrez Gene)
Chr6 NP_001184024 (RefSeq)
NM_001197095 (RefSeq)
western clawed frog serpine1 100127732 (Entrez Gene)
ChrUN XP_002941247 (RefSeq)
zebrafish serpine1 100136840 (Entrez Gene)
Chr7 NP_001108031 (RefSeq)
NM_001114559 (RefSeq)
MGI HomoloGene Information

MGI loads vertebrate homology data from NCBI HomoloGene, which programmatically detects homologs among the genome features of completely sequenced eukaryotic genomes (see: HomoloGene Build Procedure).

MGI includes homology for the following selected vertebrate species from HomoloGene:
 - human
 - mouse
 - rat
 - cattle
 - chicken
 - chimpanzee
 - dog
 - monkey, Rhesus
 - western clawed frog (Xenopus tropicalis)
 - zebrafish

These are a subset of the total species represented in HomoloGene Classes at NCBI.
Additional species may be present in an NCBI HomoloGene Class than appear in MGI.

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
MGI 6.04
The Jackson Laboratory