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Comparative GO Graph (mouse, human, rat, zebrafish)
Source
Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Hsd17b3

Graphs for Molecular Function, Cellular Component, Biological Process generated Mon Apr 26 17:39:58 2021.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

Molecular Function


Cellular Component


Biological Process



Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Hsd17b3
Category ID Classification term Gene Evidence Inferred from Organism Reference
Molecular FunctionGO:0004303estradiol 17-beta-dehydrogenase activityHsd17b3IDARatPMID:10433209|RGD:727276
Molecular FunctionGO:0047045testosterone 17-beta-dehydrogenase (NADP+) activityHSD17B3IDAHumanPMID:26545797
Molecular FunctionGO:0047045testosterone 17-beta-dehydrogenase (NADP+) activityhsd17b3IDAZfishPMID:16216911|ZFIN:ZDB-PUB-051012-25
Molecular FunctionGO:0047035testosterone dehydrogenase (NAD+) activityHsd17b3IDARatPMID:19818404|RGD:2326078
Cellular ComponentGO:0005783endoplasmic reticulumHSD17B3IDAHumanPMID:26545797
Cellular ComponentGO:0005783endoplasmic reticulumhsd17b3IDAZfishPMID:16216911|ZFIN:ZDB-PUB-051012-25
Cellular ComponentGO:0043231intracellular membrane-bounded organelleHsd17b3IDARatPMID:17936465|RGD:4889109
Cellular ComponentGO:0043231intracellular membrane-bounded organelleHsd17b3IDARatPMID:19818404|RGD:2326078
Biological ProcessGO:0006702androgen biosynthetic processhsd17b3IDAZfishPMID:16216911|ZFIN:ZDB-PUB-051012-25
Biological ProcessGO:0018879biphenyl metabolic processHsd17b3IEPRatPMID:18502095|RGD:4783624
Biological ProcessGO:0071236cellular response to antibioticHsd17b3IEPRatPMID:18655822|RGD:4777466
Biological ProcessGO:0071371cellular response to gonadotropin stimulusHsd17b3IEPRatPMID:20963569|RGD:4842495
Biological ProcessGO:0032870cellular response to hormone stimulusHsd17b3IEPRatPMID:20204307|RGD:4890944
Biological ProcessGO:0021766hippocampus developmentHsd17b3IEPRatPMID:21047951|RGD:4145527
Biological ProcessGO:0017143insecticide metabolic processHsd17b3IEPRatPMID:18401575|RGD:4890969
Biological ProcessGO:0033327Leydig cell differentiationHsd17b3IEPRatPMID:18502897|RGD:4781870
Biological ProcessGO:0006082organic acid metabolic processHsd17b3IEPRatPMID:17400581|RGD:4889129
Biological ProcessGO:0018958phenol-containing compound metabolic processHsd17b3IEPRatPMID:19429456|RGD:4890959
Biological ProcessGO:0014823response to activityHsd17b3IEPRatPMID:18923565|RGD:4890966
Biological ProcessGO:0046685response to arsenic-containing substanceHsd17b3IEPRatPMID:16483355|RGD:4889531
Biological ProcessGO:0046686response to cadmium ionHsd17b3IEPRatPMID:20957662|RGD:4890460
Biological ProcessGO:0051412response to corticosteroneHsd17b3IEPRatPMID:18335507|RGD:4831835
Biological ProcessGO:0043627response to estrogenHsd17b3IEPRatPMID:19439821|RGD:4890957
Biological ProcessGO:0045471response to ethanolHsd17b3IEPRatPMID:17193892|RGD:4889530
Biological ProcessGO:0070542response to fatty acidHsd17b3IEPRatPMID:19130109|RGD:4889519
Biological ProcessGO:0060992response to fungicideHsd17b3IEPRatPMID:17485193|RGD:4890971
Biological ProcessGO:0009635response to herbicideHsd17b3IEPRatPMID:20667998|RGD:4145533
Biological ProcessGO:0017085response to insecticideHsd17b3IEPRatPMID:20211256|RGD:4890943
Biological ProcessGO:0033591response to L-ascorbic acidHsd17b3IEPRatPMID:17280759|RGD:4891016
Biological ProcessGO:0010288response to lead ionHsd17b3IEPRatPMID:19652923|RGD:4890953
Biological ProcessGO:0010038response to metal ionHsd17b3IEPRatPMID:17822870|RGD:4890970
Biological ProcessGO:0031667response to nutrient levelsHsd17b3IEPRatPMID:17936465|RGD:4889109
Biological ProcessGO:0031667response to nutrient levelsHsd17b3IEPRatPMID:19130109|RGD:4889519
Biological ProcessGO:0014070response to organic cyclic compoundHsd17b3IEPRatPMID:18001809|RGD:4831842
Biological ProcessGO:0048545response to steroid hormoneHsd17b3IEPRatPMID:19961867|RGD:4145605
Biological ProcessGO:0033197response to vitamin EHsd17b3IEPRatPMID:17280759|RGD:4891016
Biological ProcessGO:0006694steroid biosynthetic processHsd17b3IDARatPMID:19818404|RGD:2326078

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment
  IDA Inferred from direct assay
  IEP Inferred from expression pattern
  IGI Inferred from genetic interaction
  IMP Inferred from mutant phenotype
  IPI Inferred from physical interaction
  HTP Inferred from High Throughput Experiment
  HDA Inferred from High Throughput Direct Assay
  HMP Inferred from High Throughput Mutant Phenotype
  HGI Inferred from High Throughput Genetic Interaction
  HEP Inferred from High Throughput Expression Pattern

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
05/17/2022
MGI 6.19
The Jackson Laboratory