Gene Expression Literature Summary

• Symbol: Tgm2
• Name: transglutaminase 2, C polypeptide
• ID: MGI:98731

23 matching records from 23 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.

Age	E0.5	E1	E1.5	E2	E2.5	E3	E3.5	E4	E8	E8.5	E9	E9.5	E10.5	E12.5	E13	E13.5	E14	E14.5	E15	E15.5	E16	E16.5	E17.5	E18	E18.5	E19	E19.5	E	P
Immunohistochemistry (section)													1	2		2		4		1		4	2	1	6				5
In situ RNA (section)																		4				1	1		1				1
In situ RNA (whole mount)									1	1	1
Northern blot	1	1	1	1	1	1		1																	1				2
Western blot														1		1	1	1			1		1	1	1				4
RT-PCR	1	1		1			1			1		1		2	1		1	2	1	1		1	1	2	1	1	1		6
cDNA clones																												1
Nuclease S1																													1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available

Tgm2  transglutaminase 2, C polypeptide   (Synonyms: G[a]h, protein-glutamine gamma-glutamyltransferase, TG2, TGase2, TG C, tissue transglutaminase, tTG, tTGas)
Results	Reference
8*	J:94802 Bailey CD, Johnson GV, Developmental regulation of tissue transglutaminase in the mouse forebrain. J Neurochem. 2004 Dec;91(6):1369-79
10	J:63352 Citron BA, Gregory EJ, Steigerwalt DS, Qin F, Festoff BW, Regulation of the dual function tissue transglutaminase/Galpha(h) during murine neuromuscular development: gene and enzyme isoform expression. Neurochem Int. 2000 Oct;37(4):337-49
9*	J:97957 Citron BA, Zoloty JE, Suo Z, Festoff BW, Tissue transglutaminase during mouse central nervous system development: Lack of alternative RNA processing and implications for its role(s) in murine models of neurotrauma and neurodegeneration. Brain Res Mol Brain Res. 2005 Apr 27;135(1-2):122-33
1*	J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
5	J:207219 Driskell RR, Lichtenberger BM, Hoste E, Kretzschmar K, Simons BD, Charalambous M, Ferron SR, Herault Y, Pavlovic G, Ferguson-Smith AC, Watt FM, Distinct fibroblast lineages determine dermal architecture in skin development and repair. Nature. 2013 Dec 12;504(7479):277-81
1*	J:139177 Hoffman BG, Zavaglia B, Witzsche J, Ruiz de Algara T, Beach M, Hoodless PA, Jones SJ, Marra MA, Helgason CD, Identification of transcripts with enriched expression in the developing and adult pancreas. Genome Biol. 2008;9(6):R99
6*	J:214170 Itoh M, Tatsukawa H, Eun-Seo L, Yamanishi K, Kojima S, Hitomi K, Variations in both TG1 and TG2 isozyme-specific in situ activities and protein expressions during mouse embryonic development. J Histochem Cytochem. 2013 Nov;61(11):793-801
1	J:194049 Johansson PA, Irmler M, Acampora D, Beckers J, Simeone A, Gotz M, The transcription factor Otx2 regulates choroid plexus development and function. Development. 2013 Mar;140(5):1055-66
1	J:267025 Jung H, Park H, Choi Y, Kang H, Lee E, Kweon H, Roh JD, Ellegood J, Choi W, Kang J, Rhim I, Choi SY, Bae M, Kim SG, Lee J, Chung C, Yoo T, Park H, Kim Y, Ha S, Um SM, Mo S, Kwon Y, Mah W, Bae YC, Kim H, Lerch JP, Paik SB, Kim E, Sexually dimorphic behavior, neuronal activity, and gene expression in Chd8-mutant mice. Nat Neurosci. 2018 Sep;21(9):1218-1228
8*	J:50202 Jurisicova A, Latham KE, Casper RF, Casper RF, Varmuza SL, Expression and regulation of genes associated with cell death during murine preimplantation embryo development. Mol Reprod Dev. 1998 Nov;51(3):243-53
15*	J:98561 Lee SK, Kim YS, Lee YJ, Lee SS, Song IS, Park SC, Chi JG, Chung SI, Transglutaminase 2 expression in the salivary myoepithelial cells of mouse embryo. Arch Oral Biol. 2005 Mar;50(3):301-8
1*	J:45653 Matsuki M, Yamashita F, Ishida-Yamamoto A, Yamada K, Kinoshita C, Fushiki S, Ueda E, Morishima Y, Tabata K, Yasuno H, Hashida M, Iizuka H, Ikawa M, Okabe M, Kondoh G, Kinoshita T, Takeda J, Yamanishi K, Defective stratum corneum and early neonatal death in mice lacking the gene for transglutaminase 1 (keratinocyte transglutaminase). Proc Natl Acad Sci U S A. 1998 Feb 3;95(3):1044-9
2	J:43228 Nagy L, Thomazy VA, Saydak MM, Stein JP, Davies PJ, The promoter of the mouse tissue transglutaminase gene directs tissue-specific, retinoid-regulated and apoptosis-linked expression. Cell Death Differ. 1997 Oct;4(7):534-47
1	J:285851 Nakagawa N, Yamamoto M, Imai Y, Sakaguchi Y, Takizawa T, Ohta N, Yagi N, Hatta I, Hitomi K, Takizawa T, Takeda J, Tsuda T, Matsuki M, Yamanishi K, Knocking-in the R142C mutation in transglutaminase 1 disrupts the stratum corneum barrier and postnatal survival of mice. J Dermatol Sci. 2012 Mar;65(3):196-206
1	J:100747 Ortega N, Behonick DJ, Colnot C, Cooper DN, Werb Z, Galectin-3 is a downstream regulator of matrix metalloproteinase-9 function during endochondral bone formation. Mol Biol Cell. 2005 Jun;16(6):3028-39
3	J:202654 Sauls K, de Vlaming A, Harris BS, Williams K, Wessels A, Levine RA, Slaugenhaupt SA, Goodwin RL, Pavone LM, Merot J, Schott JJ, Le Tourneau T, Dix T, Jesinkey S, Feng Y, Walsh C, Zhou B, Baldwin S, Markwald RR, Norris RA, Developmental basis for filamin-A-associated myxomatous mitral valve disease. Cardiovasc Res. 2012 Oct 1;96(1):109-19
2*	J:279119 Seow BKL, McDougall ARA, Short KL, Wallace MJ, Hooper SB, Cole TJ, Identification of Betamethasone-Regulated Target Genes and Cell Pathways in Fetal Rat Lung Mesenchymal Fibroblasts. Endocrinology. 2019 Aug 1;160(8):1868-1884
3*	J:143778 Tamplin OJ, Cox BJ, Rossant J, Integrated microarray and ChIP analysis identifies multiple Foxa2 dependent target genes in the notochord. Dev Biol. 2011 Dec 15;360(2):415-25
2*	J:145686 Tarantino U, Oliva F, Taurisano G, Orlandi A, Pietroni V, Candi E, Melino G, Maffulli N, FXIIIA and TGF-beta over-expression produces normal musculo-skeletal phenotype in TG2-/- mice. Amino Acids. 2009 Apr;36(4):679-84
1*	J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
5*	J:34526 Williams CJ, Schultz RM, Kopf GS, G protein gene expression during mouse oocyte growth and maturation, and preimplantation embryo development. Mol Reprod Dev. 1996 Jul;44(3):315-23
2	J:293760 Yu W, Yu Z, Wu D, Zhang J, Zhu Y, Zhang Y, Ning H, Wang M, Zhang J, Zhao J, Lens-specific conditional knockout of Msx2 in mice leads to ocular anterior segment dysgenesis via activation of a calcium signaling pathway. Lab Invest. 2019 Nov;99(11):1714-1727
2	J:330195 Zhou Y, Yang Y, Guo L, Qian J, Ge J, Sinner D, Ding H, Califano A, Cardoso WV, Airway basal cells show regionally distinct potential to undergo metaplastic differentiation. Elife. 2022 Sep 30;11:e80083