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Gene Expression Literature Summary
Symbol
Name
ID
Klb
klotho beta
MGI:1932466

8 matching records from 8 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E7 E9.5 E10.5 E11 E12.5 E13.5 E14.5 E15 E15.5 E17 E19.5 P
In situ RNA (section) 1 2 1 1 1
Northern blot 1 1 1 1 1
Western blot 1
RT-PCR 1 1 1 1 5

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Klb  klotho beta   (Synonyms: betaKlotho)
Results  Reference
2J:160580 Borello U, Cobos I, Long JE, McWhirter JR, Murre C, Rubenstein JL, FGF15 promotes neurogenesis and opposes FGF8 function during neocortical development. Neural Dev. 2008;3:17
9*J:65636 Ito S, Kinoshita S, Shiraishi N, Nakagawa S, Sekine S, Fujimori T, Nabeshima Y, Molecular cloning and expression analyses of mouse betaklotho, which encodes a novel klotho family protein. Mech Dev. 2000 Nov;98(1-2):115-9
3J:338938 Kobayashi K, Iwasa K, Azuma-Suzuki R, Kawauchi T, Nabeshima YI, Feto-maternal cholesterol transport regulated by beta-Klotho-FGF15 axis is essential for fetal growth. Life Sci Alliance. 2023 Oct;6(10)
2*J:274110 Nakayama Y, Masuda Y, Ohta H, Tanaka T, Washida M, Nabeshima YI, Miyake A, Itoh N, Konishi M, Fgf21 regulates T-cell development in the neonatal and juvenile thymus. Sci Rep. 2017 Mar 23;7(1):330
1J:291414 Perez-Estrada JR, Hernandez-Garcia D, Leyva-Castro F, Ramos-Leon J, Cuevas-Benitez O, Diaz-Munoz M, Castro-Obregon S, Ramirez-Solis R, Garcia C, Covarrubias L, Reduced lifespan of mice lacking catalase correlates with altered lipid metabolism without oxidative damage or premature aging. Free Radic Biol Med. 2019 May 1;135:102-115
2J:176344 Ratzka A, Baron O, Grothe C, FGF-2 deficiency does not influence FGF ligand and receptor expression during development of the nigrostriatal system. PLoS One. 2011;6(8):e23564
1J:269323 Vazquez P, Hernandez-Sanchez C, Escalona-Garrido C, Pereira L, Contreras C, Lopez M, Balsinde J, de Pablo F, Valverde AM, Increased FGF21 in brown adipose tissue of tyrosine hydroxylase heterozygous mice: implications for cold adaptation. J Lipid Res. 2018 Dec;59(12):2308-2320
1*J:199245 Vergnes L, Lee JM, Chin RG, Auwerx J, Reue K, Diet1 functions in the FGF15/19 enterohepatic signaling axis to modulate bile acid and lipid levels. Cell Metab. 2013 Jun 4;17(6):916-28

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory