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Gene Expression Literature Summary
Symbol
Name
ID
Krt6a
keratin 6A
MGI:1100845

20 matching records from 20 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E12.5 E13 E13.5 E14 E14.5 E15 E15.5 E16 E16.5 E17 E17.5 E18.5 P
Immunohistochemistry (section) 1 1 3 3 6
In situ RNA (section) 1 3 1 1 1 1
In situ RNA (whole mount) 1 1
Western blot 1
RT-PCR 1 1 2 1 2 3 6
RNase protection 1 1 1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Krt6a  keratin 6A   (Synonyms: Krt2-6a, Krt2-6c, mK6[a], MK6a)
Results  Reference
1J:93394 Adolphe C, Narang M, Ellis T, Wicking C, Kaur P, Wainwright B, An in vivo comparative study of sonic, desert and Indian hedgehog reveals that hedgehog pathway activity regulates epidermal stem cell homeostasis. Development. 2004 Oct;131(20):5009-19
8*J:129949 Cui CY, Kunisada M, Esibizione D, Grivennikov SI, Piao Y, Nedospasov SA, Schlessinger D, Lymphotoxin-beta regulates periderm differentiation during embryonic skin development. Hum Mol Genet. 2007 Nov 1;16(21):2583-90
1*J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
3J:121940 Grimm SL, Bu W, Longley MA, Roop DR, Li Y, Rosen JM, Keratin 6 is not essential for mammary gland development. Breast Cancer Res. 2006;8(3):R29
4*J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
1J:239161 Guo C, Balsara ZR, Hill WG, Li X, Stage- and subunit-specific functions of polycomb repressive complex 2 in bladder urothelial formation and regeneration. Development. 2017 Feb 01;144(3):400-408
1J:253459 Inoue SI, Takahara S, Yoshikawa T, Niihori T, Yanai K, Matsubara Y, Aoki Y, Activated Braf induces esophageal dilation and gastric epithelial hyperplasia in mice. Hum Mol Genet. 2017 Dec 1;26(23):4715-4727
3*J:216310 Jin JZ, Warner DR, Lu Q, Pisano MM, Greene RM, Ding J, Deciphering TGF-beta3 function in medial edge epithelium specification and fusion during mouse secondary palate development. Dev Dyn. 2014 Dec;243(12):1536-43
1J:86539 Kobielak K, Pasolli HA, Alonso L, Polak L, Fuchs E, Defining BMP functions in the hair follicle by conditional ablation of BMP receptor IA. J Cell Biol. 2003 Nov 10;163(3):609-23
1J:117058 Kurek D, Garinis GA, van Doorninck JH, van der Wees J, Grosveld FG, Transcriptome and phenotypic analysis reveals Gata3-dependent signalling pathways in murine hair follicles. Development. 2007 Jan;134(2):261-72
1J:102931 Li Q, Lu Q, Estepa G, Verma IM, Identification of 14-3-3sigma mutation causing cutaneous abnormality in repeated-epilation mutant mouse. Proc Natl Acad Sci U S A. 2005 Nov 1;102(44):15977-82
4*J:66533 Mazzalupo S, Coulombe PA, A reporter transgene based on a human keratin 6 gene promoter is specifically expressed in the periderm of mouse embryos. Mech Dev. 2001 Jan;100(1):65-9
2*J:81670 Mazzalupo S, Wong P, Martin P, Coulombe PA, Role for keratins 6 and 17 during wound closure in embryonic mouse skin. Dev Dyn. 2003 Feb;226(2):356-65
1J:182928 Nagarajan P, Chin SS, Wang D, Liu S, Sinha S, Garrett-Sinha LA, Ets1 blocks terminal differentiation of keratinocytes and induces expression of matrix metalloproteases and innate immune mediators. J Cell Sci. 2010 Oct 15;123(Pt 20):3566-75
2J:234993 Nishiguchi Y, Ohmoto M, Koki J, Enomoto T, Kominami R, Matsumoto I, Hirota J, Bcl11b/Ctip2 is required for development of lingual papillae in mice. Dev Biol. 2016 Aug 1;416(1):98-110
1*J:96883 Olson LE, Zhang J, Taylor H, Rose DW, Rosenfeld MG, Barx2 functions through distinct corepressor classes to regulate hair follicle remodeling. Proc Natl Acad Sci U S A. 2005 Mar 8;102(10):3708-13
4J:58385 Rothnagel JA, Seki T, Ogo M, Longley MA, Wojcik SM, Bundman DS, Bickenbach JR, Roop DR, The mouse keratin 6 isoforms are differentially expressed in the hair follicle, footpad, tongue and activated epidermis. Differentiation. 1999 Oct;65(2):119-30
2*J:147982 Sehic A, Khuu C, Risnes S, Osmundsen H, Differential gene expression profiling of the molar tooth germ in peroxisome proliferator-activated receptor-alpha (PPAR-alpha) knockout mouse and in wild-type mouse: molar tooth phenotype of PPAR-alpha knockout mouse. Eur J Oral Sci. 2009 Apr;117(2):93-104
1J:105832 Svard J, Henricson KH, Persson-Lek M, Rozell B, Lauth M, Bergstrom A, Ericson J, Toftgard R, Teglund S, Genetic elimination of suppressor of fused reveals an essential repressor function in the mammalian hedgehog signaling pathway. Dev Cell. 2006 Feb;10(2):187-97
2*J:150849 Yu Z, Mannik J, Soto A, Lin KK, Andersen B, The epidermal differentiation-associated Grainyhead gene Get1/Grhl3 also regulates urothelial differentiation. EMBO J. 2009 Jul 8;28(13):1890-903

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
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last database update
08/06/2019
MGI 6.14
The Jackson Laboratory