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Gene Expression Literature Summary
Symbol
Name
ID
Epcam
epithelial cell adhesion molecule
MGI:106653

33 matching records from 33 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E3.5 E6.5 E8.5 E9.5 E10.5 E11.5 E12.5 E13.5 E14 E14.5 E15.5 E16.5 E17.5 E18.5 A
In situ protein (section) 4 3 2 3 1 1 7 1 3 3 4 15
In situ RNA (section) 1 1 3 2 1 1
In situ protein (whole mount) 1 1 1
In situ RNA (whole mount) 1 1 3 2 2 1
In situ reporter (knock in) 1 1 1 1 1
Northern blot 1 1
Western blot 1
RT-PCR 2 2 2 1 1 4

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Epcam  epithelial cell adhesion molecule   (Synonyms: CD326, EGP-2, Egp314, EpCAM, Ep-CAM, EpCAM1, GA733-2, gp40, Ly74, panepithelial glycoprotein 314, Tacstd1, TROP1)
Results  Reference
3J:208645 Ahtiainen L, Lefebvre S, Lindfors PH, Renvoise E, Shirokova V, Vartiainen MK, Thesleff I, Mikkola ML, Directional cell migration, but not proliferation, drives hair placode morphogenesis. Dev Cell. 2014 Mar 10;28(5):588-602
2J:139649 Akiyama T, Shimo Y, Yanai H, Qin J, Ohshima D, Maruyama Y, Asaumi Y, Kitazawa J, Takayanagi H, Penninger JM, Matsumoto M, Nitta T, Takahama Y, Inoue J, The tumor necrosis factor family receptors RANK and CD40 cooperatively establish the thymic medullary microenvironment and self-tolerance. Immunity. 2008 Sep;29(3):423-37
3J:56312 Anderson R, Schaible K, Heasman J, Wylie C, Expression of the homophilic adhesion molecule, Ep-CAM, in the mammalian germ line. J Reprod Fertil. 1999 Jul;116(2):379-84
1*J:112220 Caruana G, Cullen-McEwen L, Nelson AL, Kostoulias X, Woods K, Gardiner B, Davis MJ, Taylor DF, Teasdale RD, Grimmond SM, Little MH, Bertram JF, Spatial gene expression in the T-stage mouse metanephros. Gene Expr Patterns. 2006 Dec;6(8):807-25
1J:193165 Choi E, Kraus MR, Lemaire LA, Yoshimoto M, Vemula S, Potter LA, Manduchi E, Stoeckert CJ Jr, Grapin-Botton A, Magnuson MA, Dual lineage-specific expression of Sox17 during mouse embryogenesis. Stem Cells. 2012 Oct;30(10):2297-308
1J:105207 Chu K, Tsai MJ, Neuronatin, a downstream target of BETA2/NeuroD1 in the pancreas, is involved in glucose-mediated insulin secretion. Diabetes. 2005 Apr;54(4):1064-73
1*J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
5J:195002 Guerra E, Lattanzio R, La Sorda R, Dini F, Tiboni GM, Piantelli M, Alberti S, mTrop1/Epcam knockout mice develop congenital tufting enteropathy through dysregulation of intestinal E-cadherin/beta-catenin. PLoS One. 2012;7(11):e49302
2J:189751 Hara T, Shitara S, Imai K, Miyachi H, Kitano S, Yao H, Tani-ichi S, Ikuta K, Identification of IL-7-producing cells in primary and secondary lymphoid organs using IL-7-GFP knock-in mice. J Immunol. 2012 Aug 15;189(4):1577-84
1*J:139177 Hoffman BG, Zavaglia B, Witzsche J, Ruiz de Algara T, Beach M, Hoodless PA, Jones SJ, Marra MA, Helgason CD, Identification of transcripts with enriched expression in the developing and adult pancreas. Genome Biol. 2008;9(6):R99
1J:124288 Kont V, Laan M, Kisand K, Merits A, Scott HS, Peterson P, Modulation of Aire regulates the expression of tissue-restricted antigens. Mol Immunol. 2008 Jan;45(1):25-33
10J:190580 Lei Z, Maeda T, Tamura A, Nakamura T, Yamazaki Y, Shiratori H, Yashiro K, Tsukita S, Hamada H, EpCAM contributes to formation of functional tight junction in the intestinal epithelium by recruiting claudin proteins. Dev Biol. 2012 Nov 15;371(2):136-45
3*J:162220 Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T, BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86
10J:155941 Nagao K, Zhu J, Heneghan MB, Hanson JC, Morasso MI, Tessarollo L, Mackem S, Udey MC, Abnormal placental development and early embryonic lethality in EpCAM-null mice. PLoS One. 2009;4(12):e8543
1J:207537 Nakamura K, White AJ, Parnell SM, Lane PJ, Jenkinson EJ, Jenkinson WE, Anderson G, Differential requirement for CCR4 in the maintenance but not establishment of the invariant Vgamma5(+) dendritic epidermal T-cell pool. PLoS One. 2013;8(9):e74019
1J:183911 Narhi K, Tummers M, Ahtiainen L, Itoh N, Thesleff I, Mikkola ML, Sostdc1 defines the size and number of skin appendage placodes. Dev Biol. 2012 Apr 15;364(2):149-61
3J:31296 Nelson AJ, Dunn RJ, Peach R, Aruffo A, Farr AG, The murine homolog of human Ep-CAM, a homotypic adhesion molecule, is expressed by thymocytes and thymic epithelial cells. Eur J Immunol. 1996 Feb;26(2):401-8
4J:198258 Noguchi TA, Ishimine H, Nakajima Y, Watanabe-Susaki K, Shigeta N, Yamakawa N, Wang PC, Asashima M, Kurisaki A, Novel cell surface genes expressed in the stomach primordium during gastrointestinal morphogenesis of mouse embryos. Gene Expr Patterns. 2012 Jan 15;
1J:169829 Pyrgaki C, Liu A, Niswander L, Grainyhead-like 2 regulates neural tube closure and adhesion molecule expression during neural fold fusion. Dev Biol. 2011 Mar 4;
1J:175402 Ripen AM, Nitta T, Murata S, Tanaka K, Takahama Y, Ontogeny of thymic cortical epithelial cells expressing the thymoproteasome subunit beta5t. Eur J Immunol. 2011 May;41(5):1278-87
1J:187054 Roberts NA, White AJ, Jenkinson WE, Turchinovich G, Nakamura K, Withers DR, McConnell FM, Desanti GE, Benezech C, Parnell SM, Cunningham AF, Paolino M, Penninger JM, Simon AK, Nitta T, Ohigashi I, Takahama Y, Caamano JH, Hayday AC, Lane PJ, Jenkinson EJ,Anderson G, Rank signaling links the development of invariant gammadelta T cell progenitors and Aire(+) medullary epithelium. Immunity. 2012 Mar 23;36(3):427-37
1J:124359 Rossi SW, Chidgey AP, Parnell SM, Jenkinson WE, Scott HS, Boyd RL, Jenkinson EJ, Anderson G, Redefining epithelial progenitor potential in the developing thymus. Eur J Immunol. 2007 Sep;37(9):2411-8
1J:187541 Schievenbusch S, Sauer E, Curth HM, Schulte S, Demir M, Toex U, Goeser T, Nierhoff D, Neighbor of punc e 11: expression pattern of the new hepatic stem/progenitor cell marker during murine liver development. Stem Cells Dev. 2012 Sep 20;21(14):2656-66
1J:126330 Seandel M, James D, Shmelkov SV, Falciatori I, Kim J, Chavala S, Scherr DS, Zhang F, Torres R, Gale NW, Yancopoulos GD, Murphy A, Valenzuela DM, Hobbs RM, Pandolfi PP, Rafii S, Generation of functional multipotent adult stem cells from GPR125+ germline progenitors. Nature. 2007 Sep 20;449(7160):346-50
2*J:142645 Sherwood RI, Chen TY, Melton DA, Transcriptional dynamics of endodermal organ formation. Dev Dyn. 2008 Dec 18;238(1):29-42
3J:193313 Takase HM, Itoh T, Ino S, Wang T, Koji T, Akira S, Takikawa Y, Miyajima A, FGF7 is a functional niche signal required for stimulation of adult liver progenitor cells that support liver regeneration. Genes Dev. 2013 Jan 15;27(2):169-81
13J:152812 Tanaka M, Okabe M, Suzuki K, Kamiya Y, Tsukahara Y, Saito S, Miyajima A, Mouse hepatoblasts at distinct developmental stages are characterized by expression of EpCAM and DLK1: drastic change of EpCAM expression during liver development. Mech Dev. 2009 Aug-Sep;126(8-9):665-76
3*J:132048 Trzpis M, Popa ER, McLaughlin PM, van Goor H, Timmer A, Bosman GW, de Leij LM, Harmsen MC, Spatial and temporal expression patterns of the epithelial cell adhesion molecule (EpCAM/EGP-2) in developing and adult kidneys. Nephron Exp Nephrol. 2007;107(4):e119-31
2J:182249 Tsukahara Y, Tanaka M, Miyajima A, TROP2 expressed in the trunk of the ureteric duct regulates branching morphogenesis during kidney development. PLoS One. 2011;6(12):e28607
1*J:122989 Visel A, Thaller C, Eichele G, GenePaint.org: an atlas of gene expression patterns in the mouse embryo. Nucleic Acids Res. 2004 Jan 1;32(Database issue):D552-6
1J:183539 Voutilainen M, Lindfors PH, Lefebvre S, Ahtiainen L, Fliniaux I, Rysti E, Murtoniemi M, Schneider P, Schmidt-Ullrich R, Mikkola ML, Ectodysplasin regulates hormone-independent mammary ductal morphogenesis via NF-kappaB. Proc Natl Acad Sci U S A. 2012 Apr 10;109(15):5744-9
1J:141379 Yano M, Kuroda N, Han H, Meguro-Horike M, Nishikawa Y, Kiyonari H, Maemura K, Yanagawa Y, Obata K, Takahashi S, Ikawa T, Satoh R, Kawamoto H, Mouri Y, Matsumoto M, Aire controls the differentiation program of thymic epithelial cells in the medulla for the establishment of self-tolerance. J Exp Med. 2008 Nov 24;205(12):2827-38
4J:148015 Zong Y, Panikkar A, Xu J, Antoniou A, Raynaud P, Lemaigre F, Stanger BZ, Notch signaling controls liver development by regulating biliary differentiation. Development. 2009 May;136(10):1727-39

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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory