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Gene Expression Literature Summary
cell division cycle 42

67 matching records from 67 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E0.5 E1 E2 E2.5 E3 E4 E7.5 E8.5 E9.5 E10 E10.5 E11 E11.5 E12 E12.5 E13 E13.5 E14 E14.5 E15 E15.5 E16 E16.5 E17 E17.5 E18 E18.5 E P
Immunohistochemistry (section) 1 2 1 3 1 3 1 1 2 2 1 1 1 1 1 5
In situ RNA (section) 1 1 1 3 1 1 3 1 3
Immunohistochemistry (whole mount) 2 1 1 1 2 1 1 2
In situ RNA (whole mount) 1 1 2 1 1 1 1
Western blot 1 3 1 2 1 3 1 3 1 4 2 1 3 2 2 2 5 2 18
RT-PCR 1 2 2 1 2 2 1 1 1 4 1 1 1 1 1 6
cDNA clones 1 1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Cdc42  cell division cycle 42  
Results  Reference
5*J:184022 Aizawa R, Yamada A, Suzuki D, Iimura T, Kassai H, Harada T, Tsukasaki M, Yamamoto G, Tachikawa T, Nakao K, Yamamoto M, Yamaguchi A, Aiba A, Kamijo R, Cdc42 is required for chondrogenesis and interdigital programmed cell death during limb development. Mech Dev. 2012 Mar;129(1-4):38-50
3J:125289 Backer S, Hidalgo-Sanchez M, Offner N, Portales-Casamar E, Debant A, Fort P, Gauthier-Rouviere C, Bloch-Gallego E, Trio controls the mature organization of neuronal clusters in the hindbrain. J Neurosci. 2007 Sep 26;27(39):10323-32
1J:218165 Bankhead EJ, Colasanto MP, Dyorich KM, Jamrich M, Murtaugh LC, Fuhrmann S, Multiple requirements of the focal dermal hypoplasia gene porcupine during ocular morphogenesis. Am J Pathol. 2015 Jan;185(1):197-213
1J:233988 Barry DM, Xu K, Meadows SM, Zheng Y, Norden PR, Davis GE, Cleaver O, Cdc42 is required for cytoskeletal support of endothelial cell adhesion during blood vessel formation in mice. Development. 2015 Sep 1;142(17):3058-70
1J:134927 Benninger Y, Thurnherr T, Pereira JA, Krause S, Wu X, Chrostek-Grashoff A, Herzog D, Nave KA, Franklin RJ, Meijer D, Brakebusch C, Suter U, Relvas JB, Essential and distinct roles for cdc42 and rac1 in the regulation of Schwann cell biology during peripheral nervous system development. J Cell Biol. 2007 Jun 18;177(6):1051-61
4J:141976 Bielak-Zmijewska A, Kolano A, Szczepanska K, Maleszewski M, Borsuk E, Cdc42 protein acts upstream of IQGAP1 and regulates cytokinesis in mouse oocytes and embryos. Dev Biol. 2008 Oct 1;322(1):21-32
1J:174070 Bongmba OY, Martinez LA, Elhardt ME, Butler K, Tejada-Simon MV, Modulation of dendritic spines and synaptic function by Rac1: A possible link to Fragile X syndrome pathology. Brain Res. 2011 Jul 5;1399:79-95
2J:113146 Cappello S, Attardo A, Wu X, Iwasato T, Itohara S, Wilsch-Brauninger M, Eilken HM, Rieger MA, Schroeder TT, Huttner WB, Brakebusch C, Gotz M, The Rho-GTPase cdc42 regulates neural progenitor fate at the apical surface. Nat Neurosci. 2006 Sep;9(9):1099-107
5*J:91036 Causeret F, Hidalgo-Sanchez M, Fort P, Backer S, Popoff MR, Gauthier-Rouviere C, Bloch-Gallego E, Distinct roles of Rac1/Cdc42 and Rho/Rock for axon outgrowth and nucleokinesis of precerebellar neurons toward netrin 1. Development. 2004 Jun;131(12):2841-52
3J:153957 Chauhan BK, Disanza A, Choi SY, Faber SC, Lou M, Beggs HE, Scita G, Zheng Y, Lang RA, Cdc42- and IRSp53-dependent contractile filopodia tether presumptive lens and retina to coordinate epithelial invagination. Development. 2009 Nov;136(21):3657-67
1J:121201 Chen L, Liao G, Waclaw RR, Burns KA, Linquist D, Campbell K, Zheng Y, Kuan CY, Rac1 controls the formation of midline commissures and the competency of tangential migration in ventral telencephalic neurons. J Neurosci. 2007 Apr 4;27(14):3884-93
1J:116100 Chen L, Liao G, Yang L, Campbell K, Nakafuku M, Kuan CY, Zheng Y, Cdc42 deficiency causes Sonic hedgehog-independent holoprosencephaly. Proc Natl Acad Sci U S A. 2006 Oct 31;103(44):16520-5
2J:143322 Chen Y, Stump RJ, Lovicu FJ, Shimono A, McAvoy JW, Wnt signaling is required for organization of the lens fiber cell cytoskeleton and development of lens three-dimensional architecture. Dev Biol. 2008 Dec 1;324(1):161-76
1J:148225 Corbetta S, Gualdoni S, Ciceri G, Monari M, Zuccaro E, Tybulewicz VL, de Curtis I, Essential role of Rac1 and Rac3 GTPases in neuronal development. FASEB J. 2009 May;23(5):1347-57
12J:122591 Cui XS, Li XY, Kim NH, Cdc42 is implicated in polarity during meiotic resumption and blastocyst formation in the mouse. Mol Reprod Dev. 2007 Jun;74(6):785-94
1J:171226 Cullen M, Elzarrad MK, Seaman S, Zudaire E, Stevens J, Yang MY, Li X, Chaudhary A, Xu L, Hilton MB, Logsdon D, Hsiao E, Stein EV, Cuttitta F, Haines DC, Nagashima K, Tessarollo L, St Croix B, GPR124, an orphan G protein-coupled receptor, is required for CNS-specific vascularization and establishment of the blood-brain barrier. Proc Natl Acad Sci U S A. 2011 Apr 5;108(14):5759-64
1*J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
1J:198889 El-Hashash AH, Turcatel G, Varma S, Berika M, Al Alam D, Warburton D, Eya1 protein phosphatase regulates tight junction formation in lung distal epithelium. J Cell Sci. 2012 Sep 1;125(Pt 17):4036-48
3J:234059 Elias BC, Das A, Parekh DV, Mernaugh G, Adams R, Yang Z, Brakebusch C, Pozzi A, Marciano DK, Carroll TJ, Zent R, Cdc42 regulates epithelial cell polarity and cytoskeletal function during kidney tubule development. J Cell Sci. 2015 Dec 1;128(23):4293-305
2J:211289 Fantauzzo KA, Soriano P, PI3K-mediated PDGFRalpha signaling regulates survival and proliferation in skeletal development through p53-dependent intracellular pathways. Genes Dev. 2014 May 1;28(9):1005-17
3*J:46439 Freeman TC, Dixon AK, Campbell EA, Tait TM, Richardson PJ, Rice KM, Maslen GL, Metcalfe AD, Streuli CH, Bentley DR, Expression Mapping of Mouse Genes. MGI Direct Data Submission. 1998;
1J:149918 Fuchs S, Herzog D, Sumara G, Buchmann-Moller S, Civenni G, Wu X, Chrostek-Grashoff A, Suter U, Ricci R, Relvas JB, Brakebusch C, Sommer L, Stage-specific control of neural crest stem cell proliferation by the small rho GTPases Cdc42 and Rac1. Cell Stem Cell. 2009 Mar 6;4(3):236-47
1J:161201 Gao N, Kaestner KH, Cdx2 regulates endo-lysosomal function and epithelial cell polarity. Genes Dev. 2010 Jun 15;24(12):1295-305
1*J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. http://www.gudmap.org. 2004;
3J:135577 Hartl D, Irmler M, Romer I, Mader MT, Mao L, Zabel C, de Angelis MH, Beckers J, Klose J, Transcriptome and proteome analysis of early embryonic mouse brain development. Proteomics. 2008 Mar;8(6):1257-65
3J:79013 Hayashi K, Ohshima T, Mikoshiba K, Pak1 is involved in dendrite initiation as a downstream effector of rac1 in cortical neurons. Mol Cell Neurosci. 2002 Aug;20(4):579
3J:149994 Hughes DS, Keynes RJ, Tannahill D, Extensive molecular differences between anterior- and posterior-half-sclerotomes underlie somite polarity and spinal nerve segmentation. BMC Dev Biol. 2009;9:30
2J:232103 Imai F, Ladle DR, Leslie JR, Duan X, Rizvi TA, Ciraolo GM, Zheng Y, Yoshida Y, Synapse Formation in Monosynaptic Sensory-Motor Connections Is Regulated by Presynaptic Rho GTPase Cdc42. J Neurosci. 2016 May 25;36(21):5724-35
1*J:157948 Jiang XS, Wassif CA, Backlund PS, Song L, Holtzclaw LA, Li Z, Yergey AL, Porter FD, Activation of Rho GTPases in Smith-Lemli-Opitz syndrome: pathophysiological and clinical implications. Hum Mol Genet. 2010 Apr 1;19(7):1347-57
1J:205426 Jin Y, Liu Y, Lin Q, Li J, Druso JE, Antonyak MA, Meininger CJ, Zhang SL, Dostal DE, Guan JL, Cerione RA, Peng X, Deletion of Cdc42 enhances ADAM17-mediated vascular endothelial growth factor receptor 2 shedding and impairs vascular endothelial cell survival and vasculogenesis. Mol Cell Biol. 2013 Nov;33(21):4181-97
1J:184014 Jin YR, Han XH, Taketo MM, Yoon JK, Wnt9b-dependent FGF signaling is crucial for outgrowth of the nasal and maxillary processes during upper jaw and lip development. Development. 2012 May;139(10):1821-30
1J:198772 Katayama K, Imai F, Campbell K, Lang RA, Zheng Y, Yoshida Y, RhoA and Cdc42 are required in pre-migratory progenitors of the medial ganglionic eminence ventricular zone for proper cortical interneuron migration. Development. 2013 Aug;140(15):3139-45
1J:172044 Katayama K, Melendez J, Baumann JM, Leslie JR, Chauhan BK, Nemkul N, Lang RA, Kuan CY, Zheng Y, Yoshida Y, Loss of RhoA in neural progenitor cells causes the disruption of adherens junctions and hyperproliferation. Proc Natl Acad Sci U S A. 2011 May 3;108(18):7607-12
1J:208336 Kesavan G, Lieven O, Mamidi A, Ohlin ZL, Johansson JK, Li WC, Lommel S, Greiner TU, Semb H, Cdc42/N-WASP signaling links actin dynamics to pancreatic beta cell delamination and differentiation. Development. 2014 Feb;141(3):685-96
4J:157396 Kesavan G, Sand FW, Greiner TU, Johansson JK, Kobberup S, Wu X, Brakebusch C, Semb H, Cdc42-mediated tubulogenesis controls cell specification. Cell. 2009 Nov 13;139(4):791-801
4J:221344 Kirjavainen A, Laos M, Anttonen T, Pirvola U, The Rho GTPase Cdc42 regulates hair cell planar polarity and cellular patterning in the developing cochlea. Biol Open. 2015;4(4):516-26
1J:50869 Ko MSH, Threat TA, Wang X, Horton JH, Cui Y, Pryor E, Paris J , Wells-Smith J , Kitchen JR , Rowe LB , Eppig J , Satoh T , Brant L , Fujiwara H , Yotsumoto S , Nakashima H, Genome-wide mapping of unselected transcripts from extraembryonic tissue of 7.5-day mouse embryos reveals enrichment in the t-complex and under-representation on the X chromosome. Hum Mol Genet. 1998 Nov;7(12):1967-78
1J:174742 Lehtinen MK, Zappaterra MW, Chen X, Yang YJ, Hill AD, Lun M, Maynard T, Gonzalez D, Kim S, Ye P, D'Ercole AJ, Wong ET, LaMantia AS, Walsh CA, The cerebrospinal fluid provides a proliferative niche for neural progenitor cells. Neuron. 2011 Mar 10;69(5):893-905
1J:167714 Li D, Hallett MA, Zhu W, Rubart M, Liu Y, Yang Z, Chen H, Haneline LS, Chan RJ, Schwartz RJ, Field LJ, Atkinson SJ, Shou W, Dishevelled-associated activator of morphogenesis 1 (Daam1) is required for heart morphogenesis. Development. 2011 Jan;138(2):303-15
1J:238546 Li J, Liu Y, Jin Y, Wang R, Wang J, Lu S, VanBuren V, Dostal DE, Zhang SL, Peng X, Essential role of Cdc42 in cardiomyocyte proliferation and cell-cell adhesion during heart development. Dev Biol. 2017 Jan 15;421(2):271-283
1J:181885 Liu C, Bakeri H, Li T, Swaroop A, Regulation of retinal progenitor expansion by Frizzled receptors: implications for microphthalmia and retinal coloboma. Hum Mol Genet. 2012 Apr 15;21(8):1848-60
1J:213772 Liu C, Lin C, Gao C, May-Simera H, Swaroop A, Li T, Null and hypomorph Prickle1 alleles in mice phenocopy human Robinow syndrome and disrupt signaling downstream of Wnt5a. Biol Open. 2014;3(9):861-70
1J:142220 Liu N, Bezprozvannaya S, Williams AH, Qi X, Richardson JA, Bassel-Duby R, Olson EN, microRNA-133a regulates cardiomyocyte proliferation and suppresses smooth muscle gene expression in the heart. Genes Dev. 2008 Dec 1;22(23):3242-54
2J:203790 Liu Y, Jin Y, Li J, Seto E, Kuo E, Yu W, Schwartz RJ, Blazo M, Zhang SL, Peng X, Inactivation of Cdc42 in neural crest cells causes craniofacial and cardiovascular morphogenesis defects. Dev Biol. 2013 Nov 15;383(2):239-52
1J:148322 Marcos S, Moreau J, Backer S, Job D, Andrieux A, Bloch-Gallego E, Tubulin tyrosination is required for the proper organization and pathfinding of the growth cone. PLoS One. 2009;4(4):e5405
2*J:81668 Menko AS, Kreidberg JA, Ryan TT, Van Bockstaele E, Kukuruzinska MA, Loss of alpha3beta1 integrin function results in an altered differentiation program in the mouse submandibular gland. Dev Dyn. 2001 Apr;220(4):337-49
9*J:78246 Menko AS, Zhang L, Schiano F, Kreidberg JA, Kukuruzinska MA, Regulation of cadherin junctions during mouse submandibular gland development. Dev Dyn. 2002 Jul;224(3):321-33
6J:123400 Mitchell DC, Bryan BA, Liu JP, Liu WB, Zhang L, Qu J, Zhou X, Liu M, Li DW, Developmental expression of three small GTPases in the mouse eye. Mol Vis. 2007;13:1144-53
1J:231604 Muccioli M, Qaisi D, Herman K, Plageman TF Jr, Lens placode planar cell polarity is dependent on Cdc42-mediated junctional contraction inhibition. Dev Biol. 2016 Apr 1;412(1):32-43
6*J:81328 Natale DR, Watson AJ, Rac-1 and IQGAP are potential regulators of E-cadherin-catenin interactions during murine preimplantation development. Mech Dev. 2002 Dec;119 Suppl 1:S21-6
6J:197886 Peng X, Lin Q, Liu Y, Jin Y, Druso JE, Antonyak MA, Guan JL, Cerione RA, Inactivation of Cdc42 in embryonic brain results in hydrocephalus with ependymal cell defects in mice. Protein Cell. 2013 Mar;4(3):231-42
2J:233610 Peng Y, Lu Z, Li G, Piechowicz M, Anderson M, Uddin Y, Wu J, Qiu S, The autism-associated MET receptor tyrosine kinase engages early neuronal growth mechanism and controls glutamatergic circuits development in the forebrain. Mol Psychiatry. 2016 Jul;21(7):925-35
1J:163221 Pereira JA, Benninger Y, Baumann R, Goncalves AF, Ozcelik M, Thurnherr T, Tricaud N, Meijer D, Fassler R, Suter U, Relvas JB, Integrin-linked kinase is required for radial sorting of axons and Schwann cell remyelination in the peripheral nervous system. J Cell Biol. 2009 Apr 6;185(1):147-61
2J:174208 Qian L, Wythe JD, Liu J, Cartry J, Vogler G, Mohapatra B, Otway RT, Huang Y, King IN, Maillet M, Zheng Y, Crawley T, Taghli-Lamallem O, Semsarian C, Dunwoodie S, Winlaw D, Harvey RP, Fatkin D, Towbin JA, Molkentin JD, Srivastava D, Ocorr K, Bruneau BG, Bodmer R, Tinman/Nkx2-5 acts via miR-1 and upstream of Cdc42 to regulate heart function across species. J Cell Biol. 2011 Jun 27;193(7):1181-96
1J:185948 Rosario M, Schuster S, Juttner R, Parthasarathy S, Tarabykin V, Birchmeier W, Neocortical dendritic complexity is controlled during development by NOMA-GAP-dependent inhibition of Cdc42 and activation of cofilin. Genes Dev. 2012 Aug 1;26(15):1743-57
1*J:87412 Salas-Vidal E, Lomeli H, Imaging filopodia dynamics in the mouse blastocyst. Dev Biol. 2004 Jan 1;265(1):75-89
1J:148808 Sawallisch C, Berhorster K, Disanza A, Mantoani S, Kintscher M, Stoenica L, Dityatev A, Sieber S, Kindler S, Morellini F, Schweizer M, Boeckers TM, Korte M, Scita G, Kreienkamp HJ, The insulin receptor substrate of 53 kDa (IRSp53) limits hippocampal synaptic plasticity. J Biol Chem. 2009 Apr 3;284(14):9225-36
1J:241040 Shah B, Lutter D, Tsytsyura Y, Glyvuk N, Sakakibara A, Klingauf J, Puschel AW, Rap1 GTPases Are Master Regulators of Neural Cell Polarity in the Developing Neocortex. Cereb Cortex. 2017 Feb 01;27(2):1253-1269
3J:117790 Singh S, Yin X, Pisano MM, Greene RM, Molecular profiles of mitogen activated protein kinase signaling pathways in orofacial development. Birth Defects Res A Clin Mol Teratol. 2007 Jan;79(1):35-44
2J:97223 Tunggal JA, Helfrich I, Schmitz A, Schwarz H, Gunzel D, Fromm M, Kemler R, Krieg T, Niessen CM, E-cadherin is essential for in vivo epidermal barrier function by regulating tight junctions. EMBO J. 2005 Mar 23;24(6):1146-56
1*J:147958 Vandenberg AL, Sassoon DA, Non-canonical Wnt signaling regulates cell polarity in female reproductive tract development via van gogh-like 2. Development. 2009 May;136(9):1559-70
1J:125797 Wang L, Yang L, Filippi MD, Williams DA, Zheng Y, Genetic deletion of Cdc42GAP reveals a role of Cdc42 in erythropoiesis and hematopoietic stem/progenitor cell survival, adhesion, and engraftment. Blood. 2006 Jan 1;107(1):98-105
3*J:75953 Wei L, Imanaka-Yoshida K, Wang L, Zhan S, Schneider MD, DeMayo FJ, Schwartz RJ, Inhibition of Rho family GTPases by Rho GDP dissociation inhibitor disrupts cardiac morphogenesis and inhibits cardiomyocyte proliferation. Development. 2002 Apr;129(7):1705-14
2J:105811 Wu X, Quondamatteo F, Lefever T, Czuchra A, Meyer H, Chrostek A, Paus R, Langbein L, Brakebusch C, Cdc42 controls progenitor cell differentiation and beta-catenin turnover in skin. Genes Dev. 2006 Mar 1;20(5):571-85
1J:176219 Yamauchi J, Miyamoto Y, Hamasaki H, Sanbe A, Kusakawa S, Nakamura A, Tsumura H, Maeda M, Nemoto N, Kawahara K, Torii T, Tanoue A, The atypical Guanine-nucleotide exchange factor, dock7, negatively regulates schwann cell differentiation and myelination. J Neurosci. 2011 Aug 31;31(35):12579-92
3J:235479 Yap K, Xiao Y, Friedman BA, Je HS, Makeyev EV, Polarizing the Neuron through Sustained Co-expression of Alternatively Spliced Isoforms. Cell Rep. 2016 May 10;15(6):1316-28
1J:222518 Yeung CY, Taylor SH, Garva R, Holmes DF, Zeef LA, Soininen R, Boot-Handford RP, Kadler KE, Arhgap28 is a RhoGAP that inactivates RhoA and downregulates stress fibers. PLoS One. 2014;9(9):e107036

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