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Gene Expression Literature Summary
Symbol
Name
ID
Lepr
leptin receptor
MGI:104993

17 matching records from 17 references.

Summary by Age and Assay: Numbers in the table indicate the number of results matching the search criteria.
Age E0.5 E1 E1.5 E7 E7.5 E8.5 E9.5 E10 E10.5 E11 E11.5 E12 E12.5 E13.5 E14 E14.5 E15 E15.5 E16 E16.5 E17 E17.5 E18 E18.5 E A
In situ protein (section) 1 1 1 1 1 1 1
In situ RNA (section) 1 1 3 1 2 2 2 4 1 1 3 2 1 2 1 5
In situ protein (whole mount) 1 1 1 1
Northern blot 1 1 1 1 1 1 1 1 1 1 1 1
Western blot 1 1
RT-PCR 1 2 2 2 2 2 3 1 1 3 3 6
cDNA clones 1 1

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Lepr  leptin receptor   (Synonyms: Leprb, LEPROT, leptin receptor gene-related protein, Modb1, obese-like, obl, Obr, OB-RGRP)
Results  Reference
4J:45849 Antczak M, Van Blerkom J, Oocyte influences on early development: the regulatory proteins leptin and STAT3 are polarized in mouse and human oocytes and differentially distributed within the cells of the preimplantation stage embryo. Mol Hum Reprod. 1997 Dec;3(12):1067-86
4J:76711 Camand O, Turban S, Abitbol M, Guerre-Millo M, Embryonic expression of the leptin receptor gene in mesoderm-derived tissues. C R Biol. 2002 Feb;325(2):77-87
5J:63341 Chen SC, Cunningham JJ, Smeyne RJ, Expression of OB receptor splice variants during prenatal development of the mouse. J Recept Signal Transduct Res. 2000 Jan;20(1):87-103
6*J:33785 Cioffi JA, Shafer AW, Zupancic TJ, Smith-Gbur J, Mikhail A, Platika D, Snodgrass HR, Novel B219/OB receptor isoforms: possible role of leptin in hematopoiesis and reproduction. Nat Med. 1996 May;2(5):585-9
1*J:153498 Diez-Roux G, Banfi S, Sultan M, Geffers L, Anand S, Rozado D, Magen A, Canidio E, Pagani M, Peluso I, Lin-Marq N, Koch M, Bilio M, Cantiello I, Verde R, De Masi C, Bianchi SA, Cicchini J, Perroud E, Mehmeti S, Dagand E, Schrinner S, Nurnberger A, SchmidtK, Metz K, Zwingmann C, Brieske N, Springer C, Hernandez AM, Herzog S, Grabbe F, Sieverding C, Fischer B, Schrader K, Brockmeyer M, Dettmer S, Helbig C, Alunni V, Battaini MA, Mura C, Henrichsen CN, Garcia-Lopez R, Echevarria D, Puelles E, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
3*J:46439 Freeman TC, Dixon AK, Campbell EA, Tait TM, Richardson PJ, Rice KM, Maslen GL, Metcalfe AD, Streuli CH, Bentley DR, Expression Mapping of Mouse Genes. MGI Direct Data Submission. 1998;
1J:39356 Good DJ, Porter FD, Mahon KA, Parlow AF, Westphal H, Kirsch IR, Hypogonadism and obesity in mice with a targeted deletion of the Nhlh2 gene. Nat Genet. 1997 Apr;15(4):397-401
2J:192195 Himes KP, Koppes E, Chaillet JR, Generalized disruption of inherited genomic imprints leads to wide-ranging placental defects and dysregulated fetal growth. Dev Biol. 2013 Jan 1;373(1):72-82
8J:43489 Hoggard N, Hunter L, Duncan JS, Williams LM, Trayhurn P, Mercer JG, Leptin and leptin receptor mRNA and protein expression in the murine fetus and placenta. Proc Natl Acad Sci U S A. 1997 Sep 30;94(20):11073-8
13J:74085 Hoggard N, Hunter L, Lea RG, Trayhurn P, Mercer JG, Ontogeny of the expression of leptin and its receptor in the murine fetus and placenta. Br J Nutr. 2000 Mar;83(3):317-26
3*J:102103 Jensen P, Magdaleno S, Lehman KM, Rice DS, Lavallie ER, Collins-Racie L, McCoy JM, Curran T, A neurogenomics approach to gene expression analysis in the developing brain. Brain Res Mol Brain Res. 2004 Dec 20;132(2):116-27
3*J:162220 Magdaleno S, Jensen P, Brumwell CL, Seal A, Lehman K, Asbury A, Cheung T, Cornelius T, Batten DM, Eden C, Norland SM, Rice DS, Dosooye N, Shakya S, Mehta P, Curran T, BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. PLoS Biol. 2006 Apr;4(4):e86
10*J:38697 Mikhail AA, Beck EX, Shafer A, Barut B, Gbur JS, Zupancic TJ , Schweitzer AC , Cioffi JA , Lacaud G , Ouyang B , Keller G , Snodgrass HR, Leptin stimulates fetal and adult erythroid and myeloid development. Blood. 1997 Mar 1;89(5):1507-12
2J:190524 Shalom-Barak T, Zhang X, Chu T, Timothy Schaiff W, Reddy JK, Xu J, Sadovsky Y, Barak Y, Placental PPARgamma regulates spatiotemporally diverse genes and a unique metabolic network. Dev Biol. 2012 Dec 1;372(1):143-55
3J:105139 Udagawa J, Hashimoto R, Suzuki H, Hatta T, Sotomaru Y, Hioki K, Kagohashi Y, Nomura T, Minami Y, Otani H, The role of leptin in the development of the cerebral cortex in mouse embryos. Endocrinology. 2006 Feb;147(2):647-58
12J:62930 Udagawa J, Hatta T, Naora H, Otani H, Expression of the long form of leptin receptor (Ob-Rb) mRNA in the brain of mouse embryos and newborn mice. Brain Res. 2000 Jun 23;868(2):251-8
7J:51074 Yamaguchi M, Murakami T, Yasui Y, Otani S, Kawai M, Kishi K, Kurachi H, Shima K, Aono T, Murata Y, Mouse placental cells secrete soluble leptin receptor (sOB-R): cAMP inhibits sOB-R production. Biochem Biophys Res Commun. 1998 Nov 18;252(2):363-7

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last database update
08/26/2014
MGI 5.19
The Jackson Laboratory