Automated description from the Alliance of Genome Resources
Predicted to have several functions, including ATP binding activity; misfolded protein binding activity; and unfolded protein binding activity. Involved in binding activity of sperm to zona pellucida; negative regulation of cysteine-type endopeptidase activity involved in apoptotic process; and response to heat. Localizes to the cell body; mitochondrion; and zona pellucida receptor complex. Predicted to colocalize with the COP9 signalosome. Human ortholog(s) of this gene implicated in several diseases, including brain ischemia; obesity; senile cataract; toxic shock syndrome; and type 2 diabetes mellitus. Orthologous to human HSPA1B (heat shock protein family A (Hsp70) member 1B).