Automated description from the Alliance of Genome Resources (Release 3.2)
Exhibits connexin binding activity and protein domain specific binding activity. Involved in several processes, including negative regulation of stress fiber assembly; positive regulation of sprouting angiogenesis; and sensory perception of sound. Localizes to several cellular components, including apicolateral plasma membrane; bicellular tight junction; and intercellular canaliculus. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; genitourinary system; and sensory organ. Orthologous to human TJP1 (tight junction protein 1).