Tjp1 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Tjp1
tight junction protein 1
MGI:98759

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0008013	beta-catenin binding	ISO	J:155856
Molecular Function	GO:0005516	calmodulin binding	IEA	J:60000
Molecular Function	GO:0050839	cell adhesion molecule binding	IBA	J:265628
Molecular Function	GO:0071253	connexin binding	IPI	J:240293
Molecular Function	GO:0071253	connexin binding	IPI	J:240292
Molecular Function	GO:0005515	protein binding	IPI	J:117470
Molecular Function	GO:0005515	protein binding	IPI	J:102192
Molecular Function	GO:0005515	protein binding	IPI	J:58914
Molecular Function	GO:0005515	protein binding	IPI	J:208850
Molecular Function	GO:0005515	protein binding	IPI	J:169070
Molecular Function	GO:0005515	protein binding	IPI	J:200309
Molecular Function	GO:0005515	protein binding	IPI	J:212352
Molecular Function	GO:0005515	protein binding	IPI	J:212352
Molecular Function	GO:0005515	protein binding	IPI	J:227841
Molecular Function	GO:0019904	protein domain specific binding	IPI	J:124995
Molecular Function	GO:0044325	transmembrane transporter binding	ISO	J:155856
Cellular Component	GO:0005912	adherens junction	IDA	J:73293
Cellular Component	GO:0005912	adherens junction	IDA	J:124995
Cellular Component	GO:0005912	adherens junction	IDA	J:78857
Cellular Component	GO:0005912	adherens junction	IDA	J:73293
Cellular Component	GO:0005912	adherens junction	IDA	J:101707
Cellular Component	GO:0043296	apical junction complex	ISO	J:105556
Cellular Component	GO:0045177	apical part of cell	IDA	J:199301
Cellular Component	GO:0045177	apical part of cell	ISO	J:73065
Cellular Component	GO:0045177	apical part of cell	IDA	J:202984
Cellular Component	GO:0045177	apical part of cell	IDA	J:197681
Cellular Component	GO:0045177	apical part of cell	IDA	J:197573
Cellular Component	GO:0016324	apical plasma membrane	IDA	J:180706
Cellular Component	GO:0016327	apicolateral plasma membrane	IDA	J:107229
Cellular Component	GO:0016323	basolateral plasma membrane	ISO	J:105556
Cellular Component	GO:0005923	bicellular tight junction	IDA	J:172996
Cellular Component	GO:0005923	bicellular tight junction	ISO	J:155856
Cellular Component	GO:0005923	bicellular tight junction	IBA	J:265628
Cellular Component	GO:0005923	bicellular tight junction	IDA	J:104866
Cellular Component	GO:0005923	bicellular tight junction	IDA	J:117589
Cellular Component	GO:0005923	bicellular tight junction	IDA	J:216935
Cellular Component	GO:0005923	bicellular tight junction	IDA	J:137091
Cellular Component	GO:0005923	bicellular tight junction	IDA	J:89901
Cellular Component	GO:0005923	bicellular tight junction	IDA	J:99397
Cellular Component	GO:0005923	bicellular tight junction	IDA	J:56425
Cellular Component	GO:0005923	bicellular tight junction	IDA	J:143865
Cellular Component	GO:0005923	bicellular tight junction	IDA	J:117344
Cellular Component	GO:0005923	bicellular tight junction	IDA	J:201580
Cellular Component	GO:0005923	bicellular tight junction	IDA	J:117056
Cellular Component	GO:0005923	bicellular tight junction	IDA	J:169219
Cellular Component	GO:0005923	bicellular tight junction	IDA	J:200284
Cellular Component	GO:0005923	bicellular tight junction	IDA	J:161201
Cellular Component	GO:0005923	bicellular tight junction	IDA	J:164933
Cellular Component	GO:0005923	bicellular tight junction	IDA	J:99397
Cellular Component	GO:0005923	bicellular tight junction	IDA	J:127113
Cellular Component	GO:0005923	bicellular tight junction	IDA	J:73641
Cellular Component	GO:0005923	bicellular tight junction	IDA	J:89901
Cellular Component	GO:0005923	bicellular tight junction	IDA	J:119866
Cellular Component	GO:0005923	bicellular tight junction	IDA	J:99397
Cellular Component	GO:0005923	bicellular tight junction	IDA	J:89901
Cellular Component	GO:0005923	bicellular tight junction	IDA	J:103553
Cellular Component	GO:0005923	bicellular tight junction	IDA	J:97223
Cellular Component	GO:0005923	bicellular tight junction	IDA	J:119178
Cellular Component	GO:0005923	bicellular tight junction	IDA	J:107229
Cellular Component	GO:0005923	bicellular tight junction	IDA	J:87877
Cellular Component	GO:0005923	bicellular tight junction	IDA	J:156525
Cellular Component	GO:0005923	bicellular tight junction	IDA	J:72801
Cellular Component	GO:0005923	bicellular tight junction	IDA	J:65401
Cellular Component	GO:0005923	bicellular tight junction	IDA	J:124995
Cellular Component	GO:0005923	bicellular tight junction	IDA	J:114313
Cellular Component	GO:0005923	bicellular tight junction	ISO	J:105556
Cellular Component	GO:0005923	bicellular tight junction	ISO	J:73065
Cellular Component	GO:0005923	bicellular tight junction	IDA	J:89901
Cellular Component	GO:0030054	cell junction	ISO	J:164563
Cellular Component	GO:0030054	cell junction	IDA	J:105556
Cellular Component	GO:0030054	cell junction	IDA	J:177528
Cellular Component	GO:0030054	cell junction	IDA	J:182969
Cellular Component	GO:0009986	cell surface	ISO	J:81857
Cellular Component	GO:0005911	cell-cell junction	ISO	J:155856
Cellular Component	GO:0005911	cell-cell junction	IDA	J:279948
Cellular Component	GO:0005911	cell-cell junction	IDA	J:207520
Cellular Component	GO:0005911	cell-cell junction	IDA	J:227841
Cellular Component	GO:0005911	cell-cell junction	IDA	J:199456
Cellular Component	GO:0005911	cell-cell junction	IDA	J:199456
Cellular Component	GO:0005911	cell-cell junction	IDA	J:161641
Cellular Component	GO:0005911	cell-cell junction	IDA	J:136803
Cellular Component	GO:0005911	cell-cell junction	IDA	J:213985
Cellular Component	GO:0005911	cell-cell junction	IDA	J:159723
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	IDA	J:105556
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005921	gap junction	ISO	J:155856
Cellular Component	GO:0014704	intercalated disc	IDA	J:140247
Cellular Component	GO:0046581	intercellular canaliculus	IDA	J:77485
Cellular Component	GO:0016020	membrane	IDA	J:98502
Cellular Component	GO:0005634	nucleus	IDA	J:279948
Cellular Component	GO:0005634	nucleus	IDA	J:87877
Cellular Component	GO:0005634	nucleus	IDA	J:105556
Cellular Component	GO:0005886	plasma membrane	IDA	J:240293
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	IDA	J:81857
Cellular Component	GO:0005886	plasma membrane	ISO	J:135985
Cellular Component	GO:0005886	plasma membrane	IDA	J:81857
Cellular Component	GO:0005886	plasma membrane	IDA	J:97223
Cellular Component	GO:0005886	plasma membrane	IDA	J:90107
Cellular Component	GO:0005886	plasma membrane	IDA	J:81857
Cellular Component	GO:0005886	plasma membrane	IDA	J:81857
Cellular Component	GO:0005886	plasma membrane	IDA	J:81857
Cellular Component	GO:0005886	plasma membrane	IDA	J:77501
Cellular Component	GO:0005886	plasma membrane	IDA	J:123097
Cellular Component	GO:0005886	plasma membrane	IDA	J:81857
Cellular Component	GO:0005886	plasma membrane	IDA	J:81857
Cellular Component	GO:0032991	protein-containing complex	ISO	J:164563
Cellular Component	GO:0032991	protein-containing complex	IMP	J:240292
Cellular Component	GO:0070160	tight junction	IDA	J:280385
Cellular Component	GO:0070160	tight junction	ISO	J:164563
Cellular Component	GO:0070160	tight junction	IDA	J:308050
Cellular Component	GO:0070160	tight junction	ISO	J:300338
Cellular Component	GO:0070160	tight junction	IDA	J:230002
Biological Process	GO:0031032	actomyosin structure organization	ISO	J:164563
Biological Process	GO:0034334	adherens junction maintenance	ISO	J:164563
Biological Process	GO:0001825	blastocyst formation	IMP	J:136803
Biological Process	GO:0098609	cell-cell adhesion	IBA	J:265628
Biological Process	GO:0045216	cell-cell junction organization	ISO	J:164563
Biological Process	GO:0045216	cell-cell junction organization	IBA	J:265628
Biological Process	GO:0090557	establishment of endothelial intestinal barrier	ISO	J:164563
Biological Process	GO:0090557	establishment of endothelial intestinal barrier	IBA	J:265628
Biological Process	GO:2000250	negative regulation of actin cytoskeleton reorganization	ISO	J:164563
Biological Process	GO:0043066	negative regulation of apoptotic process	ISO	J:164563
Biological Process	GO:0051497	negative regulation of stress fiber assembly	IMP	J:283200
Biological Process	GO:1905605	positive regulation of blood-brain barrier permeability	ISO	J:164563
Biological Process	GO:1905605	positive regulation of blood-brain barrier permeability	IBA	J:265628
Biological Process	GO:0030335	positive regulation of cell migration	ISO	J:164563
Biological Process	GO:0008284	positive regulation of cell population proliferation	ISO	J:164563
Biological Process	GO:2000049	positive regulation of cell-cell adhesion mediated by cadherin	ISO	J:164563
Biological Process	GO:1903672	positive regulation of sprouting angiogenesis	IMP	J:283200
Biological Process	GO:1903672	positive regulation of sprouting angiogenesis	ISO	J:164563
Biological Process	GO:0071896	protein localization to adherens junction	ISO	J:164563
Biological Process	GO:1902396	protein localization to bicellular tight junction	ISO	J:164563
Biological Process	GO:0150105	protein localization to cell-cell junction	ISO	J:164563
Biological Process	GO:0150105	protein localization to cell-cell junction	IMP	J:283200
Biological Process	GO:0150105	protein localization to cell-cell junction	IBA	J:265628
Biological Process	GO:2000810	regulation of bicellular tight junction assembly	ISO	J:164563
Biological Process	GO:1901888	regulation of cell junction assembly	ISO	J:164563
Biological Process	GO:0051493	regulation of cytoskeleton organization	ISO	J:164563
Biological Process	GO:0007605	sensory perception of sound	IMP	J:201580

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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