Automated description from the Alliance of Genome Resources
Exhibits several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II regulatory region sequence-specific DNA binding activity; and protein heterodimerization activity. Involved in several processes, including hemopoiesis; regulation of myeloid cell differentiation; and regulation of transcription by RNA polymerase II. Localizes to the nucleus and transcription factor complex. Predicted to colocalize with the Lsd1/2 complex and histone deacetylase complex. Used to study lymphocytic leukemia. Human ortholog(s) of this gene implicated in precursor lymphoblastic lymphoma/leukemia. Is expressed in several structures, including cardiovascular system; central nervous system; extraembryonic component; hemolymphoid system; and sensory organ. Orthologous to human TAL1 (TAL bHLH transcription factor 1, erythroid differentiation factor).