Automated description from the Alliance of Genome Resources
Exhibits scaffold protein binding activity and voltage-gated sodium channel activity involved in SA node cell action potential. Involved in several processes, including calcium ion homeostasis; cardiac ventricle development; and regulation of heart contraction. Localizes to several cellular components, including the T-tubule; lateral plasma membrane; and sodium channel complex. Used to study Brugada syndrome 1; dilated cardiomyopathy 1E; long QT syndrome 3; and progressive familial heart block type IA. Human ortholog(s) of this gene implicated in heart conduction disease (multiple); intrinsic cardiomyopathy (multiple); and sudden infant death syndrome. Orthologous to human SCN5A (sodium voltage-gated channel alpha subunit 5).