Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits voltage-gated sodium channel activity. Involved in several processes, including intrinsic apoptotic signaling pathway in response to osmotic stress; memory; and neuron apoptotic process. Localizes to several cellular components, including T-tubule; integral component of presynaptic membrane; and paranode region of axon. Is expressed in brain; heart; sciatic nerve; sympathetic ganglion; and telencephalon. Human ortholog(s) of this gene implicated in benign familial neonatal epilepsy and early infantile epileptic encephalopathy 11. Orthologous to human SCN2A (sodium voltage-gated channel alpha subunit 2).