Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including camera-type eye morphogenesis; circulatory system development; and positive regulation of cell differentiation. Acts upstream of or within several processes, including epithelial cell differentiation; hepatocyte cell migration; and regulation of transcription by RNA polymerase II. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; brain; branchial arch; cardiovascular system; and sensory organ. Used to study dilated cardiomyopathy and obesity. Orthologous to human PROX1 (prospero homeobox 1).