Automated description from the Alliance of Genome Resources (Release 3.2)
Exhibits kinase binding activity. Involved in several processes, including embryonic placenta development; muscle cell cellular homeostasis; and trans-synaptic signaling by BDNF, modulating synaptic transmission. Localizes to Schaffer collateral - CA1 synapse; extrinsic component of plasma membrane; and glutamatergic synapse. Is expressed in early conceptus; embryo; liver; and secondary oocyte. Human ortholog(s) of this gene implicated in COVID-19; conjunctivitis; myocardial infarction; plasminogen deficiency type I; and thrombophilia. Orthologous to several human genes including PLG (plasminogen).