Automated description from the Alliance of Genome Resources
Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II proximal promoter sequence-specific DNA binding activity; and protein heterodimerization activity. Predicted to contribute to RNA polymerase II regulatory region sequence-specific DNA binding activity. Involved in several processes, including animal organ development; positive regulation of G2/M transition of mitotic cell cycle; and regionalization. Localizes to the cytoplasm; nucleus; and transcription factor complex. Human ortholog(s) of this gene implicated in precursor B lymphoblastic lymphoma/leukemia. Is expressed in several structures, including alimentary system; brain; branchial arch; embryo mesenchyme; and genitourinary system. Orthologous to human PBX1 (PBX homeobox 1).