Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to contribute to RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including animal organ development; positive regulation of G2/M transition of mitotic cell cycle; and regionalization. Localizes to cytoplasm; nucleus; and transcription regulator complex. Is expressed in several structures, including alimentary system; branchial arch; central nervous system; embryo mesenchyme; and genitourinary system. Human ortholog(s) of this gene implicated in B-lymphoblastic leukemia/lymphoma. Orthologous to human PBX1 (PBX homeobox 1).