Automated description from the Alliance of Genome Resources (Release 3.1)
Exhibits RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; chromatin binding activity; and identical protein binding activity. Involved in several processes, including cellular response to dsRNA; cellular response to tumor necrosis factor; and regulation of macromolecule biosynthetic process. Localizes to cytosol and nucleus. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; nose; and respiratory system. Human ortholog(s) of this gene implicated in breast cancer; common variable immunodeficiency; lung non-small cell carcinoma; melanoma; and prostate cancer. Orthologous to human NFKB1 (nuclear factor kappa B subunit 1).