Automated description from the Alliance of Genome Resources (Release 3.2)
Exhibits several functions, including ionotropic glutamate receptor binding activity; protein phosphorylated amino acid binding activity; and sodium channel inhibitor activity. Involved in several processes, including cellular protein metabolic process; circulatory system development; and negative regulation of vascular endothelial growth factor receptor signaling pathway. Localizes to several cellular components, including dendritic spine; glutamatergic synapse; and postsynaptic cytosol. Is expressed in several structures, including alimentary system; eye; limb; nervous system; and respiratory system. Orthologous to human NEDD4 (NEDD4 E3 ubiquitin protein ligase).