Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables DNA-binding transcription factor activity; chromatin binding activity; and sequence-specific DNA binding activity. Involved in nervous system development and regulation of transcription by RNA polymerase II. Acts upstream of or within several processes, including brain development; musculoskeletal movement, spinal reflex action; and neurogenesis. Located in neuronal cell body and nucleus. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; peripheral nervous system; and sensory organ. Orthologous to human ASCL1 (achaete-scute family bHLH transcription factor 1).