Automated description from the Alliance of Genome Resources
Exhibits growth hormone receptor binding activity and protein tyrosine kinase activity. Involved in several processes, including cell surface receptor signaling pathway; cellular response to cytokine stimulus; and positive regulation of receptor signaling pathway via STAT. Predicted to localize to the cytoplasm and nucleus. Used to study systemic lupus erythematosus. Human ortholog(s) of this gene implicated in pancreatic adenocarcinoma. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; hemolymphoid system gland; and liver and biliary system. Orthologous to human JAK1 (Janus kinase 1).