Automated description from the Alliance of Genome Resources (Release 4.2.0)
Predicted to enable G protein-coupled receptor binding activity and integrin binding activity. Predicted to contribute to insulin-like growth factor I binding activity and neuregulin binding activity. Acts upstream of or within several processes, including filopodium assembly; peripheral nervous system myelin formation; and trophoblast cell migration. Located in several cellular components, including basal plasma membrane; basement membrane; and hemidesmosome. Part of integrin complex. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and sensory organ. Used to study junctional epidermolysis bullosa non-Herlitz type and junctional epidermolysis bullosa with pyloric atresia. Human ortholog(s) of this gene implicated in junctional epidermolysis bullosa non-Herlitz type and junctional epidermolysis bullosa with pyloric atresia. Orthologous to human ITGB4 (integrin subunit beta 4).
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