Automated description from the Alliance of Genome Resources (Release 3.2)
Predicted to contribute to insulin-like growth factor I binding activity and neuregulin binding activity. Involved in several processes, including filopodium assembly; peripheral nervous system myelin formation; and trophoblast cell migration. Localizes to several cellular components, including basal plasma membrane; hemidesmosome; and integrin complex. Is expressed in several structures, including alimentary system; brain; genitourinary system; integumental system; and sensory organ. Used to study junctional epidermolysis bullosa non-Herlitz type and junctional epidermolysis bullosa with pyloric atresia. Human ortholog(s) of this gene implicated in epidermolysis bullosa simplex localized type; junctional epidermolysis bullosa non-Herlitz type; and junctional epidermolysis bullosa with pyloric atresia. Orthologous to human ITGB4 (integrin subunit beta 4).