GO Annotations Graph

• Symbol: Itgb4
• Name: integrin beta 4
• ID: MGI:96613

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0001664	G protein-coupled receptor binding	ISO	J:164563
Molecular Function	GO:0031994	insulin-like growth factor I binding	ISO	J:164563
Molecular Function	GO:0005178	integrin binding	IBA	J:265628
Molecular Function	GO:0038132	neuregulin binding	ISO	J:164563
Molecular Function	GO:0005515	protein binding	IPI	J:261524
Molecular Function	GO:0005515	protein binding	IPI	J:104989
Molecular Function	GO:0005515	protein binding	IPI	J:261524
Molecular Function	GO:0005515	protein binding	IPI	J:104989
Molecular Function	GO:0005515	protein binding	IPI	J:104989
Cellular Component	GO:0009925	basal plasma membrane	IDA	J:171374
Cellular Component	GO:0009925	basal plasma membrane	IDA	J:75058
Cellular Component	GO:0005604	basement membrane	IDA	J:116050
Cellular Component	GO:0005938	cell cortex	ISO	J:155856
Cellular Component	GO:0030054	cell junction	ISO	J:164563
Cellular Component	GO:0031252	cell leading edge	ISO	J:164563
Cellular Component	GO:0009986	cell surface	ISO	J:164563
Cellular Component	GO:0009986	cell surface	IBA	J:265628
Cellular Component	GO:0009986	cell surface	IDA	J:104989
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005925	focal adhesion	IBA	J:265628
Cellular Component	GO:0098978	glutamatergic synapse	ISO	J:155856
Cellular Component	GO:0030056	hemidesmosome	ISO	J:164563
Cellular Component	GO:0030056	hemidesmosome	IDA	J:181275
Cellular Component	GO:0030056	hemidesmosome	IDA	J:174237
Cellular Component	GO:0008305	integrin complex	IBA	J:265628
Cellular Component	GO:0008305	integrin complex	IDA	J:77644
Cellular Component	GO:0016020	membrane	ISO	J:155856
Cellular Component	GO:0031965	nuclear membrane	ISO	J:164563
Cellular Component	GO:0005730	nucleolus	ISO	J:164563
Cellular Component	GO:0005886	plasma membrane	ISO	J:164563
Cellular Component	GO:0045211	postsynaptic membrane	ISO	J:155856
Cellular Component	GO:0043235	receptor complex	ISO	J:194542
Biological Process	GO:0006914	autophagy	ISO	J:164563
Biological Process	GO:0007155	cell adhesion	IMP	J:77644
Biological Process	GO:0033627	cell adhesion mediated by integrin	IBA	J:265628
Biological Process	GO:0007154	cell communication	IEA	J:72247
Biological Process	GO:0016477	cell migration	IBA	J:265628
Biological Process	GO:0048870	cell motility	ISO	J:164563
Biological Process	GO:0007160	cell-matrix adhesion	ISO	J:164563
Biological Process	GO:0007160	cell-matrix adhesion	IBA	J:265628
Biological Process	GO:0046847	filopodium assembly	IMP	J:108325
Biological Process	GO:0031581	hemidesmosome assembly	ISO	J:164563
Biological Process	GO:0007229	integrin-mediated signaling pathway	IBA	J:265628
Biological Process	GO:0022011	myelination in peripheral nervous system	IGI	J:261524
Biological Process	GO:0035878	nail development	ISO	J:164563
Biological Process	GO:0032290	peripheral nervous system myelin formation	IGI	J:261524
Biological Process	GO:0009611	response to wounding	ISO	J:164563
Biological Process	GO:0043589	skin morphogenesis	ISO	J:164563
Biological Process	GO:0061450	trophoblast cell migration	IMP	J:174237