Automated description from the Alliance of Genome Resources (Release 3.1.1)
Predicted to have several functions, including insulin-like growth factor binding activity; peptide binding activity; and purine ribonucleoside triphosphate binding activity. Involved in several processes, including animal organ development; positive regulation of cell cycle; and positive regulation of macromolecule biosynthetic process. Localizes to caveola. Predicted to colocalize with cell body; dendrite; and nucleus. Is expressed in several structures, including adrenal gland; decidua; enteric nervous system; heart; and liver. Human ortholog(s) of this gene implicated in Donohue syndrome; diabetes mellitus (multiple); familial hyperinsulinemic hypoglycemia 5; hepatocellular carcinoma; and reproductive organ cancer (multiple). Orthologous to human INSR (insulin receptor).