Automated description from the Alliance of Genome Resources (Release 3.2)
Exhibits insulin-like growth factor binding activity. Involved in several processes, including gland development; positive regulation of cell cycle; and regulation of intracellular signal transduction. Localizes to T-tubule and integral component of membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; limb; and lung. Human ortholog(s) of this gene implicated in several diseases, including dementia (multiple); kidney cancer (multiple); liver disease (multiple); nervous system cancer (multiple); and neurodegenerative disease (multiple). Orthologous to human IGF1R (insulin like growth factor 1 receptor).