Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in embryonic skeletal system development; muscle structure development; and pharyngeal system development. Acts upstream of or within several processes, including regionalization; regulation of transcription by RNA polymerase II; and rhombomere development. Located in nucleus. Is expressed in several structures, including alimentary system; branchial arch; central nervous system; genitourinary system; and sensory organ. Orthologous to human HOXA2 (homeobox A2).