Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables glucokinase activity and peptidoglycan binding activity. Involved in canonical glycolysis; positive regulation of cytokine production involved in immune response; and positive regulation of interleukin-1 beta production. Acts upstream of or within carbohydrate phosphorylation. Located in cytosol; membrane raft; and mitochondrion. Is expressed in several structures, including alimentary system; integumental system; nervous system; respiratory system; and sensory organ. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 4G; anemia (multiple); hematologic cancer (multiple); obesity; and retinitis pigmentosa. Orthologous to human HK1 (hexokinase 1).