Automated description from the Alliance of Genome Resources
Exhibits misfolded protein binding activity and ribosome binding activity. Involved in several processes, including IRE1-mediated unfolded protein response; cellular response to interleukin-4; and cerebellum development. Localizes to several cellular components, including the endoplasmic reticulum; endoplasmic reticulum-Golgi intermediate compartment; and plasma membrane. Predicted to colocalize with the COP9 signalosome. Human ortholog(s) of this gene implicated in dopamine beta-hydroxylase deficiency. Orthologous to human HSPA5 (heat shock protein family A (Hsp70) member 5).