Hspa5 GO Annotations Graph

GO Annotations Graph

Symbol
Name
ID

Hspa5
heat shock protein 5
MGI:95835

GO annotations (Text View) (Tabular View)

A table of the annotations represented in this image is provided below.

Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
Graph generated Fri Mar 10 20:53:16 2023.

Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP: Inferred from experiment
HMP: Inferred from high throughput mutant phenotype
HGI: Inferred from high throughput genetic interaction
HDA: Inferred from high throughput direct assay
HEP: Inferred from high throughput expression pattern
IDA: Inferred from direct assay
IEP: Inferred from expression pattern
IGI: Inferred from genetic interaction
IMP: Inferred from mutant phenotype
IPI: Inferred from physical interaction

Homology:

IAS: Inferred from ancestral sequence
IBA: Inferred from biological aspect of ancestor
IBD: Inferred from biological aspect of descendant
IKR: Inferred from key residues
IMR: Inferred from missing residues
IRD: Inferred from rapid divergence
ISA: Inferred from sequence alignment
ISM: Inferred from sequence model
ISO: Inferred from sequence orthology
ISS: Inferred from sequence or structural similarity

Automated:

IEA: Inferred from electronic annotation
RCA: Reviewed computational analysis

Other:

IC: Inferred by curator
NAS: Non-traceable author statement
ND: No biological data available
TAS: Traceable author statement

Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0005524	ATP binding	ISO	J:164563
Molecular Function	GO:0016887	ATP hydrolysis activity	ISO	J:164563
Molecular Function	GO:0016887	ATP hydrolysis activity	IBA	J:265628
Molecular Function	GO:0140662	ATP-dependent protein folding chaperone	IEA	J:72247
Molecular Function	GO:0019899	enzyme binding	ISO	J:164563
Molecular Function	GO:0031072	heat shock protein binding	IBA	J:265628
Molecular Function	GO:0016787	hydrolase activity	IEA	J:60000
Molecular Function	GO:0051787	misfolded protein binding	IDA	J:156044
Molecular Function	GO:0051787	misfolded protein binding	ISO	J:164563
Molecular Function	GO:0051787	misfolded protein binding	ISO	J:200660
Molecular Function	GO:0000166	nucleotide binding	IEA	J:60000
Molecular Function	GO:0005515	protein binding	IPI	J:108290
Molecular Function	GO:0005515	protein binding	IPI	J:156044
Molecular Function	GO:0005515	protein binding	IPI	J:76352
Molecular Function	GO:0005515	protein binding	IPI	J:144475
Molecular Function	GO:0005515	protein binding	IPI	J:108337
Molecular Function	GO:0005515	protein binding	IPI	J:215393
Molecular Function	GO:0005515	protein binding	IPI	J:313853
Molecular Function	GO:0005515	protein binding	IPI	J:247398
Molecular Function	GO:0005515	protein binding	IPI	J:217277
Molecular Function	GO:0005515	protein binding	IPI	J:289677
Molecular Function	GO:0005515	protein binding	IPI	J:88977
Molecular Function	GO:0005515	protein binding	IPI	J:188369
Molecular Function	GO:0005515	protein binding	IPI	J:208508
Molecular Function	GO:0005515	protein binding	IPI	J:77390
Molecular Function	GO:0005515	protein binding	IPI	J:130239
Molecular Function	GO:0005515	protein binding	IPI	J:193640
Molecular Function	GO:0019904	protein domain specific binding	ISO	J:164563
Molecular Function	GO:0044183	protein folding chaperone	IBA	J:265628
Molecular Function	GO:0044183	protein folding chaperone	IDA	J:193993
Molecular Function	GO:0043022	ribosome binding	IDA	J:77390
Molecular Function	GO:0031625	ubiquitin protein ligase binding	ISO	J:164563
Molecular Function	GO:0051082	unfolded protein binding	ISO	J:155856
Cellular Component	GO:0009986	cell surface	IDA	J:130239
Cellular Component	GO:0008180	COP9 signalosome	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:164563
Cellular Component	GO:0005737	cytoplasm	ISO	J:155856
Cellular Component	GO:0005737	cytoplasm	IBA	J:265628
Cellular Component	GO:0005829	cytosol	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:164563
Cellular Component	GO:0005783	endoplasmic reticulum	IDA	J:217277
Cellular Component	GO:0005783	endoplasmic reticulum	IDA	J:92692
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:149519
Cellular Component	GO:0005783	endoplasmic reticulum	IDA	J:186473
Cellular Component	GO:0005783	endoplasmic reticulum	IDA	J:224971
Cellular Component	GO:0005783	endoplasmic reticulum	IDA	J:148339
Cellular Component	GO:0005783	endoplasmic reticulum	IDA	J:4119
Cellular Component	GO:0005783	endoplasmic reticulum	IDA	J:88977
Cellular Component	GO:0005783	endoplasmic reticulum	IDA	J:110647
Cellular Component	GO:0005783	endoplasmic reticulum	ISO	J:104449
Cellular Component	GO:0005783	endoplasmic reticulum	IDA	J:83641
Cellular Component	GO:0005783	endoplasmic reticulum	IDA	J:199864
Cellular Component	GO:0005783	endoplasmic reticulum	IDA	J:85668
Cellular Component	GO:0005783	endoplasmic reticulum	IDA	J:203279
Cellular Component	GO:0005783	endoplasmic reticulum	IDA	J:230059
Cellular Component	GO:0005783	endoplasmic reticulum	IDA	J:93423
Cellular Component	GO:0034663	endoplasmic reticulum chaperone complex	IDA	J:217288
Cellular Component	GO:0034663	endoplasmic reticulum chaperone complex	ISO	J:164563
Cellular Component	GO:0034663	endoplasmic reticulum chaperone complex	IBA	J:265628
Cellular Component	GO:0005788	endoplasmic reticulum lumen	ISO	J:164563
Cellular Component	GO:0005788	endoplasmic reticulum lumen	IDA	J:158036
Cellular Component	GO:0005788	endoplasmic reticulum lumen	TAS	Reactome:R-MMU-351337
Cellular Component	GO:0005788	endoplasmic reticulum lumen	IBA	J:265628
Cellular Component	GO:0005789	endoplasmic reticulum membrane	ISO	J:164563
Cellular Component	GO:0005789	endoplasmic reticulum membrane	IDA	J:188369
Cellular Component	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment	ISO	J:164563
Cellular Component	GO:0005793	endoplasmic reticulum-Golgi intermediate compartment	IDA	J:169417
Cellular Component	GO:0005576	extracellular region	TAS	Reactome:R-MMU-351337
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	ISO	J:164563
Cellular Component	GO:0016020	membrane	IBA	J:265628
Cellular Component	GO:0016020	membrane	ISO	J:200660
Cellular Component	GO:0030496	midbody	ISO	J:164563
Cellular Component	GO:0005739	mitochondrion	ISO	J:155856
Cellular Component	GO:0005739	mitochondrion	ISO	J:164563
Cellular Component	GO:0043209	myelin sheath	HDA	J:145263
Cellular Component	GO:0005634	nucleus	ISO	J:164563
Cellular Component	GO:0005634	nucleus	IBA	J:265628
Cellular Component	GO:0005886	plasma membrane	IDA	J:208508
Cellular Component	GO:0032991	protein-containing complex	ISO	J:164563
Cellular Component	GO:0005790	smooth endoplasmic reticulum	ISO	J:155856
Biological Process	GO:0042149	cellular response to glucose starvation	ISO	J:164563
Biological Process	GO:0071353	cellular response to interleukin-4	IDA	J:62630
Biological Process	GO:0021680	cerebellar Purkinje cell layer development	IMP	J:158036
Biological Process	GO:0021589	cerebellum structural organization	IMP	J:158036
Biological Process	GO:0051085	chaperone cofactor-dependent protein refolding	IBA	J:265628
Biological Process	GO:0030968	endoplasmic reticulum unfolded protein response	IMP	J:158036
Biological Process	GO:0030968	endoplasmic reticulum unfolded protein response	IBA	J:265628
Biological Process	GO:0006983	ER overload response	IDA	J:74700
Biological Process	GO:0036498	IRE1-mediated unfolded protein response	IEP	J:210646
Biological Process	GO:0035437	maintenance of protein localization in endoplasmic reticulum	ISO	J:164563
Biological Process	GO:0043066	negative regulation of apoptotic process	ISO	J:164563
Biological Process	GO:0030512	negative regulation of transforming growth factor beta receptor signaling pathway	IGI	J:130239
Biological Process	GO:0030335	positive regulation of cell migration	ISO	J:164563
Biological Process	GO:0040019	positive regulation of embryonic development	TAS	J:158036
Biological Process	GO:0010976	positive regulation of neuron projection development	ISO	J:155856
Biological Process	GO:0031398	positive regulation of protein ubiquitination	IMP	J:158036
Biological Process	GO:0031204	post-translational protein targeting to membrane, translocation	ISO	J:164563
Biological Process	GO:0042026	protein refolding	IBA	J:265628
Biological Process	GO:0051603	proteolysis involved in protein catabolic process	IDA	J:156044
Biological Process	GO:0034976	response to endoplasmic reticulum stress	ISO	J:200660
Biological Process	GO:1901998	toxin transport	IMP	J:197389
Biological Process	GO:0030433	ubiquitin-dependent ERAD pathway	IBA	J:265628

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 05/14/2024 MGI 6.23