Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables extracellularly glutamate-gated ion channel activity; glutamate-gated receptor activity; and transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential. Acts upstream of or within chemical synaptic transmission. Located in several cellular components, including perisynaptic space; postsynaptic density membrane; and synaptic vesicle membrane. Part of AMPA glutamate receptor complex. Is active in Schaffer collateral - CA1 synapse and glutamatergic synapse. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; liver and biliary system; and sensory organ. Orthologous to human GRIA2 (glutamate ionotropic receptor AMPA type subunit 2).