Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits extracellularly glutamate-gated ion channel activity; ionotropic glutamate receptor activity; and transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential. Involved in chemical synaptic transmission. Localizes to several cellular components, including Schaffer collateral - CA1 synapse; integral component of plasma membrane; and synaptic vesicle membrane. Is expressed in several structures, including alimentary system; central nervous system; eye; genitourinary system; and skeletal musculature. Orthologous to human GRIA2 (glutamate ionotropic receptor AMPA type subunit 2).