Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables GMP binding activity and GTPase activity. Involved in several processes, including cytolysis in another organism; positive regulation of pyroptosis; and response to bacterium. Acts upstream of or within adhesion of symbiont to host; cellular response to interferon-beta; and defense response to other organism. Located in cytoplasmic vesicle and symbiont-containing vacuole membrane. Orthologous to several human genes including GBP2 (guanylate binding protein 2).