Automated description from the Alliance of Genome Resources
Exhibits fibroblast growth factor-activated receptor activity. Involved in several processes, including MAPK cascade; animal organ development; and positive regulation of protein modification process. Localizes to the cytoplasmic side of plasma membrane; lysosome; and perinuclear region of cytoplasm. Used to study Muenke Syndrome; achondroplasia; scoliosis; and thanatophoric dysplasia. Human ortholog(s) of this gene implicated in several diseases, including LADD syndrome; SADDAN; acanthosis nigricans; bone disease (multiple); and camptodactyly-tall stature-scoliosis-hearing loss syndrome. Orthologous to human FGFR3 (fibroblast growth factor receptor 3).