Automated description from the Alliance of Genome Resources
Predicted to contribute to growth factor binding activity. Involved in several processes, including negative regulation of immature T cell proliferation in thymus; nervous system development; and positive regulation of macromolecule metabolic process. Localizes to the apical plasma membrane; cytoplasmic vesicle; and myelin sheath. Used to study Hirschsprung's disease; breast cancer; and dilated cardiomyopathy. Human ortholog(s) of this gene implicated in malignant glioma; mammary Paget's disease; prostate cancer; renal cell carcinoma; and urinary bladder cancer. Orthologous to human ERBB2 (erb-b2 receptor tyrosine kinase 2).