Automated description from the Alliance of Genome Resources (Release 7.0.0)
Predicted to enable guanyl-nucleotide exchange factor activity and translation initiation factor binding activity. Predicted to contribute to translation initiation factor activity. Predicted to be involved in several processes, including T cell receptor signaling pathway; cytoplasmic translational initiation; and nervous system development. Predicted to act upstream of or within translation. Predicted to be located in cytoplasm. Predicted to be part of eukaryotic translation initiation factor 2B complex. Is expressed in several structures, including adipose tissue; brain; eye; gut gland; and male reproductive gland or organ. Used to study leukoencephalopathy with vanishing white matter. Human ortholog(s) of this gene implicated in leukoencephalopathy with vanishing white matter 4. Orthologous to human EIF2B4 (eukaryotic translation initiation factor 2B subunit delta).