Automated description from the Alliance of Genome Resources
Exhibits complement binding activity and serine-type endopeptidase inhibitor activity. Predicted to be involved in negative regulation of complement activation, lectin pathway and negative regulation of endopeptidase activity. Localizes to the extracellular space. Human ortholog(s) of this gene implicated in angioedema (multiple); cerebral infarction; macular degeneration; pancreatitis; and toxic shock syndrome. Is expressed in genitourinary system; neural ectoderm; notochord; and pancreas mesenchyme. Orthologous to human SERPING1 (serpin family G member 1).