Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables extracellular matrix binding activity and integrin binding activity. Acts upstream of or within several processes, including chondroblast differentiation; circulatory system development; and regulation of apoptotic process. Located in collagen-containing extracellular matrix. Is expressed in several structures, including brain; embryo mesenchyme; heart; sensory organ; and skeleton. Used to study atrial heart septal defect 1 and atrioventricular septal defect. Human ortholog(s) of this gene implicated in high grade glioma. Orthologous to human CCN1 (cellular communication network factor 1).