GO Annotations Graph

• Symbol: Ccn1
• Name: cellular communication network factor 1
• ID: MGI:88613

GO annotations

A table of the annotations represented in this image is provided below.

• Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
• Experimental annotations are indicated by darker-colored nodes; other annotations by lighter-colored nodes
• Clicking on any node links to the MGI GO browser and information on all genes annotated to the term or its subterms.
• Graph generated Fri Mar 10 20:53:16 2023.

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Gene Ontology Evidence Code Abbreviations:

Experimental:

EXP Inferred from experiment

HMP Inferred from high throughput mutant phenotype

HGI Inferred from high throughput genetic interaction

HDA Inferred from high throughput direct assay

HEP Inferred from high throughput expression pattern

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

Homology:

IAS Inferred from ancestral sequence

IBA Inferred from biological aspect of ancestor

IBD Inferred from biological aspect of descendant

IKR Inferred from key residues

IMR Inferred from missing residues

IRD Inferred from rapid divergence

ISA Inferred from sequence alignment

ISM Inferred from sequence model

ISO Inferred from sequence orthology

ISS Inferred from sequence or structural similarity

Automated:

IEA Inferred from electronic annotation

RCA Reviewed computational analysis

Other:

IC Inferred by curator

NAS Non-traceable author statement

ND No biological data available

TAS Traceable author statement

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Category	GO ID	Classification Term	Evidence	Reference
Molecular Function	GO:0050840	extracellular matrix binding	IDA	J:139122
Molecular Function	GO:0019838	growth factor binding	IEA	J:60000
Molecular Function	GO:0008201	heparin binding	IEA	J:60000
Molecular Function	GO:0005178	integrin binding	IDA	J:85278
Cellular Component	GO:0062023	collagen-containing extracellular matrix	HDA	J:213088
Cellular Component	GO:0005576	extracellular region	IEA	J:60000
Cellular Component	GO:0005576	extracellular region	IEA	J:72247
Biological Process	GO:0006915	apoptotic process	IMP	J:126490
Biological Process	GO:0003278	apoptotic process involved in heart morphogenesis	IMP	J:126490
Biological Process	GO:0060413	atrial septum morphogenesis	IMP	J:126490
Biological Process	GO:0003181	atrioventricular valve morphogenesis	IMP	J:126490
Biological Process	GO:0007155	cell adhesion	ISO	J:155856
Biological Process	GO:0007155	cell adhesion	IDA	J:85278
Biological Process	GO:0098609	cell-cell adhesion	IDA	J:45322
Biological Process	GO:0006935	chemotaxis	ISO	J:155856
Biological Process	GO:0060591	chondroblast differentiation	IDA	J:45322
Biological Process	GO:0060591	chondroblast differentiation	IDA	J:45322
Biological Process	GO:0060710	chorio-allantoic fusion	IMP	J:80618
Biological Process	GO:0030198	extracellular matrix organization	IDA	J:139122
Biological Process	GO:0002041	intussusceptive angiogenesis	IMP	J:80618
Biological Process	GO:0060716	labyrinthine layer blood vessel development	IMP	J:80618
Biological Process	GO:0043066	negative regulation of apoptotic process	IMP	J:126490
Biological Process	GO:0001649	osteoblast differentiation	IGI	J:107256
Biological Process	GO:0043065	positive regulation of apoptotic process	IGI	J:149902
Biological Process	GO:0043065	positive regulation of apoptotic process	IGI	J:149902
Biological Process	GO:0043065	positive regulation of apoptotic process	IGI	J:149902
Biological Process	GO:0043065	positive regulation of apoptotic process	IGI	J:149902
Biological Process	GO:0030513	positive regulation of BMP signaling pathway	ISO	J:164563
Biological Process	GO:0030501	positive regulation of bone mineralization	ISO	J:164563
Biological Process	GO:0061036	positive regulation of cartilage development	IMP	J:45322
Biological Process	GO:0045597	positive regulation of cell differentiation	IDA	J:45322
Biological Process	GO:0030335	positive regulation of cell migration	ISO	J:164563
Biological Process	GO:0030335	positive regulation of cell migration	IDA	J:107256
Biological Process	GO:0010811	positive regulation of cell-substrate adhesion	IDA	J:139122
Biological Process	GO:2000304	positive regulation of ceramide biosynthetic process	IDA	J:149902
Biological Process	GO:2000343	positive regulation of chemokine (C-X-C motif) ligand 2 production	ISO	J:155856
Biological Process	GO:0043280	positive regulation of cysteine-type endopeptidase activity involved in apoptotic process	IGI	J:149902
Biological Process	GO:0032731	positive regulation of interleukin-1 beta production	ISO	J:155856
Biological Process	GO:0032740	positive regulation of interleukin-17 production	ISO	J:155856
Biological Process	GO:0032755	positive regulation of interleukin-6 production	ISO	J:155856
Biological Process	GO:0045669	positive regulation of osteoblast differentiation	ISO	J:164563
Biological Process	GO:0033690	positive regulation of osteoblast proliferation	ISO	J:164563
Biological Process	GO:0010518	positive regulation of phospholipase activity	IDA	J:149902
Biological Process	GO:0045860	positive regulation of protein kinase activity	ISO	J:164563
Biological Process	GO:0001934	positive regulation of protein phosphorylation	ISO	J:164563
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ISO	J:164563
Biological Process	GO:2000309	positive regulation of tumor necrosis factor (ligand) superfamily member 11 production	ISO	J:155856
Biological Process	GO:0032760	positive regulation of tumor necrosis factor production	ISO	J:155856
Biological Process	GO:0072593	reactive oxygen species metabolic process	IDA	J:149902
Biological Process	GO:0070372	regulation of ERK1 and ERK2 cascade	ISO	J:164563
Biological Process	GO:0007165	signal transduction	IEA	J:72247
Biological Process	GO:0003281	ventricular septum development	IMP	J:126490
Biological Process	GO:0044319	wound healing, spreading of cells	ISO	J:164563