Automated description from the Alliance of Genome Resources (Release 4.0)
Involved in several processes, including cellular response to hypoxia; complement activation; and negative regulation of complement activation. Localizes to basolateral plasma membrane and external side of plasma membrane. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system; and liver and biliary system. Human ortholog(s) of this gene implicated in malaria. Orthologous to several human genes including CR1L (complement C3b/C4b receptor 1 like).