Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables several functions, including ephrin receptor binding activity; signaling receptor complex adaptor activity; and ubiquitin protein ligase binding activity. Involved in several processes, including positive regulation of Rac protein signal transduction; positive regulation of skeletal muscle acetylcholine-gated channel clustering; and postsynaptic specialization assembly. Acts upstream of or within several processes, including helper T cell diapedesis; nervous system development; and reelin-mediated signaling pathway. Located in actin cytoskeleton and membrane. Is active in neuromuscular junction. Is expressed in several structures, including central nervous system; embryo mesenchyme; genitourinary system; immune system; and musculature. Orthologous to human CRK (CRK proto-oncogene, adaptor protein).