Automated description from the Alliance of Genome Resources (Release 5.2.2)
Predicted to enable heparan sulfate binding activity and heparin binding activity. Predicted to be an extracellular matrix structural constituent. Acts upstream of or within several processes, including collagen fibril organization; skeletal system development; and ventricular cardiac muscle tissue morphogenesis. Located in extracellular matrix. Part of collagen trimer. Is expressed in several structures, including alimentary system; heart; limb; sensory organ; and skeleton. Used to study Stickler syndrome and osteoarthritis. Human ortholog(s) of this gene implicated in Marshall syndrome; Stickler syndrome 2; autosomal dominant nonsyndromic deafness; and fibrochondrogenesis 1. Orthologous to human COL11A1 (collagen type XI alpha 1 chain).