Automated description from the Alliance of Genome Resources (Release 3.1.1)
Exhibits anion binding activity; ion channel binding activity; and molecular function regulator. Involved in several processes, including negative regulation of sodium ion transmembrane transport; positive regulation of nitrogen compound metabolic process; and positive regulation of synaptic growth at neuromuscular junction. Localizes to several cellular components, including cell surface; sarcolemma; and synaptic cleft. Is expressed in several structures, including lower jaw; nervous system; notochord; retina; and skeletal musculature. Used to study congenital myasthenic syndrome 8. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome 8. Orthologous to human AGRN (agrin).