Automated description from the Alliance of Genome Resources (Release 7.0.0)
Enables G protein-coupled receptor kinase activity. Involved in negative regulation of relaxation of smooth muscle. Acts upstream of or within several processes, including G protein-coupled receptor signaling pathway; desensitization of G protein-coupled receptor signaling pathway; and regulation of the force of heart contraction. Located in membrane. Is expressed in several structures, including central nervous system; genitourinary system; heart; limb; and mesenchyme derived from neural crest. Orthologous to human GRK2 (G protein-coupled receptor kinase 2).