Automated description from the Alliance of Genome Resources (Release 3.2)
Exhibits G protein-coupled receptor kinase activity. Involved in several processes, including desensitization of G protein-coupled receptor signaling pathway; negative regulation of relaxation of smooth muscle; and protein phosphorylation. Localizes to membrane. Is expressed in several structures, including central nervous system; genitourinary system; heart; limb; and mesenchyme derived from neural crest. Orthologous to human GRK2 (G protein-coupled receptor kinase 2).