Automated description from the Alliance of Genome Resources (Release 4.0)
Predicted to enable acetylcholine binding activity and acetylcholine-gated cation-selective channel activity. Predicted to contribute to acetylcholine receptor activity. Involved in regulation of synaptic vesicle exocytosis. Acts upstream of or within response to nicotine. Part of acetylcholine-gated channel complex. Is active in dopaminergic synapse. Is expressed in gut; lung; nervous system; and thymus. Human ortholog(s) of this gene implicated in lung cancer. Orthologous to human CHRNA5 (cholinergic receptor nicotinic alpha 5 subunit).